Showing papers by "Bareilly College published in 1983"

Phorate and mexacarbate induced changes in enzymes of the snail,Lymnaea acuminata

Abstract: The snailLymnaea acuminata, vector of the liver flukesFasciola hepatica andFasciola gigantica, was exposed to 40% and 80% LC50 doses of the pesticides 12/24 mg/L phorate (O,O-diethylS-(ethylthio) methyl phosphorodithioate) and 2.5/5.0 mg/L of mexacarbate (4-dimethylamino)-3,5-dimethylphenyl methyl carbamate) for 24 or 48 hr. These pesticides, although considered to be antiacetylcholinesterase agents, inhibited alkaline phosphatase and enhanced the activity of acid phosphatase in hepatopancreas, mantle, intestine, and foot of the snail. Trypsin activity in the alimentary canal of the snail was also inhibited. Discontinuation of pesticide treatment resulted in partial recovery in mexacarbate-treated animals while in phorate-treated animals the effect of the pesticide was largely irreversible.