Showing papers by "BIA Separations (Slovenia) published in 2015"
TL;DR: This review gives an overview on thenanoplex downstream challenges and chromatography based analytical methods for efficient monitoring of the nanoplex production.
Abstract: Downstream processing of nanoplexes (viruses, virus-like particles, bacteriophages) is characterized by complexity of the starting material, number of purification methods to choose from, regulations that are setting the frame for the final product and analytical methods for upstream and downstream monitoring. This review gives an overview on the nanoplex downstream challenges and chromatography based analytical methods for efficient monitoring of the nanoplex production.
55 citations
TL;DR: Development of a hydrophobic methacrylate monolith with improved resolution for pDNA isoforms separation and removal of host contaminants and usage of pyridine-modified monoliths resulted in a more efficient separation between p DNA isoforms.
14 citations
TL;DR: This first separation of individual viruses from an artificially prepared laboratory mixture should encourage new applications of monolithic chromatographic supports in the separation of plant, bacterial, or animal viruses from all kinds of mixed samples.
13 citations
TL;DR: The obtained results confirm that methacrylate monoliths can be a valuable tool for simultaneous removal of different waterborne viruses from contaminated water sources.
11 citations
TL;DR: SDC is identified as a promising new approach to large-scale pDNA purification, which is compatible with continuous, multicolumn chromatography systems, and could therefore be used to increase productivity of pDNA production in the future.
11 citations