Showing papers by "Binzhou Medical College published in 1996"
Journal Article•
TL;DR: This study proved that the administration of oxytocin with the feedback pulsatile Oxytocin system is easier to establish the effective uterine contraction, and it is a more physiologic and effective regimen for induction of labor.
Abstract: OBJECTIVE: To improve the safety and the effect on induction of labor with oxytocin. METHOD: 112 cases were selected for labor induction with feedback pulsatile oxytocin under the monitoring of uterine contraction controller (study group). 112 cases were selected with continuous intravenous infusion of oxytocin as a control (control group). The dose of oxytocin and the pulse time-point were adjusted. The effects of labor induction in the 2 groups were compared. RESULTS: The most suitable time-point was 1.5 minute after the uterine contraction. The best administration duration was 20 seconds. But the most suitable dose varied individually, generally 12-25 mU. The mean time to establish contraction in study group was significantly shorter (1.9 +/- 1.2 min) than that of the control group (115.5 +/- 72.3 min, P < 0.001). The average dose of oxytocin administered per hour was significantly less in the study group (312 +/- 64 mU) than that of the control group (735 +/- 125 mU, P < 0.001) the success rate was 100% in study group whereas only 90.2% in control group (P < 0.01). The total duration of labor in the study group was 6.9 +/- 4.7 hours in contrast to 20.4 +/- 10.9 hours in the control group (P < 0.001). The occurrences of dystocia, postpartum hemorrhage and neonatal asphyxia were lower in study group. CONCLUSION: This study proved that the administration of oxytocin with the feedback pulsatile oxytocin system is easier to establish the effective uterine contraction, and it is a more physiologic and effective regimen for induction of labor.
2 citations
Journal Article•
TL;DR: The increasing of serum PLAP may be helpful for the diagnosis of malignant tumors especially ovarian cancer because it shows deviative distribution.
Abstract: OBJECTIVE To establish a method for diagnosis of malignant tumors by determination of the placental alkaline phosphatase (PLAP) in serum. METHODS A solid phase enzyme immunoassay was adopated by an antibody against PLAP. PLAP in serum of 81 patients with malignant tumor and 86 healthy people as control were determined. RESULTS In the control group, the PLAP activity showed deviative distribution, the 95th percentile values of PLAP in control group was 3.8U/L. If this value served as normal cut-off line, 18 cases among 81 patients with malignant tumors were positive. The positive rate was 22.2%, but the positive rates in ovarian cancer was 61.9%. CONCLUSIONS The increasing of serum PLAP may be helpful for the diagnosis of malignant tumors especially ovarian cancer.
2 citations
Journal Article•
TL;DR: The results demonstrated that ILP with over maximum tolerence dosage of (MTD) 5-FU resulted in irreversible damage of liver and endothelial cells.
Abstract: To observe the pathological changes of liver sinusoidal endothelial cells, the regional perfusion with different dosage of 5-FU was performed by using modified rat's model of ILP. The results demonstrated that ILP with over maximum tolerence dosage of (MTD) 5-FU resulted in irreversible damage of liver and endothelial cells. The endothelial cells were more fragile than liver cells. The changes of TXA2 and PGI2 balance play an important role in the process of damage of endothelial cells.
1 citations