Showing papers by "Central University of Ecuador published in 2000"
Journal Article•
TL;DR: Oxygen pressure is lower in geographical high altitude; several placental changes have been informed associated to high altitude such decreased weight, low oxygen diffusion, increased throphoblastic cells, sincitial knots and fetal capillaries and reduced blood volume.
Abstract: Oxygen pressure is lower in geographical high altitude; several placental changes have been informed associated to high altitude such decreased weight, low oxygen diffusion, increased throphoblastic cells, sincitial knots and fetal capillaries and reduced blood volume. Placental changes contribute to preclampsia and premature deliveries. A deep-slow respiratory pattern, no ventilation changes, and vagal phasic high inspiratory/low expiratory Hering-Breuer reflex characterize cardiorespiratory adaptations. The impact on heart rate is mild, only an increased beat interval is observed. Slowed fetal growth contribute to decreased birth weight as follows: from 102 to 130 g after a critical altitude point of 2 000 m over the sea level or 105 g per each 50 mm Hg of atmospheric pressure. Hemoglobin increases 4% per each 100 m of altitude and the risk of polycythemia is also increased. Postnatal growth is retarded until 2 years of age. Cleflip, microtia, branchial arch anomalies, amniotic bands, rectal atresia, and craniosinostosis are most frequently found in high altitude. Cooling and over protection against it, decrease stimulation and development of infants. Altitude high; congenital defects; cardiorespiratory adaptation.
6 citations