Showing papers by "Deen Dayal Upadhyay Gorakhpur University published in 1991"
TL;DR: Nath et al. as discussed by the authors measured the vapour pressure for binary liquid mixtures of methylethylketone with methylene chloride 1,2-dichloroethane, trichloroencane, tetrachloroethene and cyclohexane.
6 citations
TL;DR: In this paper, the hydrodynamic and electrodriven permeability of sodium chloride and magnesium chloride solutions was studied using cellulose acetate and Dowex 50 membranes with and without a lecithin liquid membrane.
6 citations
TL;DR: In this paper, perturbative configuration interaction using localized orbitals (PCILO) computations were done on two β-blockers, namely, acetophenone- O - (tert-butylamino-3-hydroxy-2-propyl) oxime (ABHPO) and BHPIF.
Abstract: The conformations of drugs and receptors play a very important role in determining their biological properties. In order to understand the role of the conformation of β-adrenergic blocking agents, perturbative configuration interaction using localized orbitals (PCILO) computations were done on two β-blockers, namely, acetophenone- O - (tert-butylamino-3-hydroxy-2-propyl) oxime (ABHPO) and ( tert -butylamino-3-hydroxy-2-propylimino)-9-fluorene (BHPIF). The results indicate a folded conformation for ABHPO due to intramolecular hydrogen bonding, while the preferred conformation for BHPIF is an extended one. The biological significance of these results was analysed in the light of our earlier studies on propranolol which is the most potent β-blocking drug.
4 citations