Showing papers by "Hai phong University Of Medicine and Pharmacy published in 2003"
TL;DR: No recommendations can be made on the use of mannitol in acute stroke, and properly randomized, controlled trials should be performed to come to a final conclusion.
Abstract: Background and Purpose— Mannitol is used worldwide to treat acute stroke, although its efficacy and safety have not been proven by randomized trials. Methods— In a tricenter, prospective study, we analyzed the 30-day and 1-year case fatality with respect to mannitol treatment status in 805 patients consecutively admitted within 72 hours of stroke onset. Confounding factors were compared between treated and nontreated patients. Results— Two thirds of the patients received intravenous mannitol as part of their routine treatment (mean dose, 47±22 g/d; mean duration, 6±3 days). The case fatality was 25% versus 16% (P=0.006) at 30 days and 38% versus 25% (P<0.001) at 1 year in the-mannitol treated and nontreated groups, respectively. Mannitol treatment effect was adjusted for age, stroke severity, fever in the first 3 days, and aspirin treatment (for ischemic strokes) in logistic regression models. Depending on the factors entered into the model, either no effect or harm could be attributed to mannitol. When t...
49 citations
01 Jan 2003
TL;DR: In USA, Sweden and United Kingdom the pulmonary embolism is the main cause of maternal death due to medical complications and the morbidity represented by CVI as a result of DVT at pregnant women is 35%.
Abstract: In USA, Sweden and United Kingdom the pulmonary embolism is the main cause of maternal death due to medical complications. The morbidity represented by CVI as a result of DVT at pregnant women is 35%.