Showing papers by "Oklahoma City University published in 1971"
TL;DR: The diamino acid transport systems of T. cruzi have undergone major evolutionary modifications and at least one arginine transport site is so specific that homoarginine will not react with it.
Abstract: SYNOPSIS. Arginine in Trypanosoma cruzi is taken up by a mediated transport system; a large non-saturable component is also involved. Arginine transport specificity in T. cruzi is unusual since lysine and histidine do not inhibit its uptake. Glycine and valine are partially competitive inhibitors and homoarginine, alanine and methionine are completely competitive. At least one arginine transport site is so specific that homoarginine will not react with it. Apparently the diamino acid transport systems of T. cruzi have undergone major evolutionary modifications.
16 citations
TL;DR: The distribution of 14C from uniformly labelled, 1-14C labelled and 3- 14C labelled serine within amino acid-containing metabolic fractions demonstrates that T. cruzi is able to synthesize several amino acids with serine as a precursor.
Abstract: 1.
1. The use of serine as a precursor of other amino acids by Trypanosoma cruzi has been studied.
2.
2. The distribution of 14C from uniformly labelled, 1-14C labelled and 3-14C labelled serine within amino acid-containing metabolic fractions demonstrates that T. cruzi is able to synthesize several amino acids (alanine, aspartate, glutamate, glycine, cysteine, threonine) with serine as a precursor.
5 citations