Showing papers by "Pan American Health Organization published in 1979"
TL;DR: A low incidence of coronary heart disease in this community of Salt Cay, Turks and Caicos Isles is indicated, and the lipoprotein lipid pattern in these people is consistent with a low cardiovascular risk status, and might account for the apparent absence of coronaryHeart disease on the island.
Abstract: Fasting serum high-density lipoprotein (HDL) cholesterol, other lipid concentrations and related characteristics have been measured in 87% of 261 residents aged over 5 years on the small isolated island of Salt Cay, Turks and Caicos Isles. Only one subject, a hypertensive woman, had a major electrocardiographic Q wave abnormality, and none of the islanders had clinical coronary heart disease. These findings, together with local clinical experience indicated a low incidence of coronary heart disease in this community. Adult mean concentrations of HDL cholesterol (1.6 mmol/l) and serum total triglyceride (0.81 mmol/l) were relatively high and low respectively compared with those of men and women in North American communities. Unlike findings in North America, there was no significant sex difference in HDL cholesterol concentration apparent in adulthood and this was not explained by sex differences in alcohol consumption (positively correlated with HDL cholesterol in both sexes) or adiposity (negatively correlated with HDL cholesterol in men only). Residents who were recovering from an epidemic of mild upper respiratory infection had on average a 9% reduction in HDL cholesterol concentration compared with the remainder of the community. The lipoprotein lipid pattern in these people is consistent with a low cardiovascular risk status, and might account for the apparent absence of coronary heart disease on the island.
17 citations
TL;DR: It is suggested that a loss of T-cell regulatory mechanism may explain the results of the homocytotropic antibody response to unrelated antigens of mice with acute or chronic infection with Trypanosoma cruzi.
3 citations
01 Jan 1979
TL;DR: In this paper, the authors report that there is distressingly little information available on program benefits with which to design or redesign service delivery systems, and design decisions based on facts are increasingly important, however, both in terms of anticipating resource requirements and ultimately, assuring that benefits accrue to target populations.
Abstract: Although health and nutrition services are expanding rapidly in Latin America and other low income regions around the world, surprisingly little is known about the various impacts of these services on the program recipients. Particularly, there is distressingly little information available on program benefits with which to design or redesign service delivery systems. Design decisions based on facts are increasingly important, however, both in terms of anticipating resource requirements and ultimately in terms of assuring that benefits accrue to target populations.