Showing papers by "Sunnybrook Health Sciences Centre published in 1986"
TL;DR: A detailed review of 104 patients with severe nasoethmoid-orbital injuries has facilitated the classification of these injuries into five types and the use of craniofacial surgical techniques and immediate bone graft replacement of missing or severely damaged bone will allow reconstruction of even the most difficult injuries in one stage.
Abstract: A detailed review of 104 patients with severe nasoethmoid-orbital injuries has facilitated the classification of these injuries into five types. The recognition and diagnosis of each specific injury pattern will define the correct treatment choice in each instance. Special attention should be focused on injuries with comminution and bone loss in the medial wall and floor of the orbit, loss of cartilaginous nasal support, and orbital displacement and dystopia. An open, direct approach to these fractures with meticulous reduction, internal fixation, and repair of the medial canthal ligaments provides optimal repair. The use of craniofacial surgical techniques and immediate bone graft replacement of missing or severely damaged bone will allow reconstruction of even the most difficult injuries in one stage. Three hundred and nine primary bone grafts have been used in 66 patients. No significant complications of their use have occurred.
47 citations
TL;DR: Recent studies have confirmed that relatively low doses of thiazide diuretics may effectively lower blood pressure in elderly hypertensive patients while causing fewer biochemical abnormalities than previously associated with the use of these drugs.
Abstract: Recent studies have confirmed the benefits of treating hypertension in the elderly. Thiazide diuretics appear to be effective in achieving goal blood pressure in a majority of patients above the age of 60 years. Increasing concern regarding the biochemical abnormalities associated with diuretic therapy has led to the more widespread use of lower doses of these agents. Preliminary results from a study of hydrochlorothiazide ±amiloride treatment in 99 hypertensive patients aged 65 to 80 years indicate that hydrochlorothiazide 25 to 50 mg/day will lower diastolic blood pressure to less than 90mm Hg in about 90% of elderly patients with mild to moderate elevations in blood pressure. These lower dosages of hydrochlorothiazide were only occasionally associated with mild hypokalaemia. However, the addition of amiloride to the treatment regimen resulted in the maintenance of normal serum potassium concentrations. Thus, relatively low doses of thiazide diuretics may effectively lower blood pressure in elderly hypertensive patients while causing fewer biochemical abnormalities than previously associated with the use of these drugs.
5 citations