Showing papers by "Sunnybrook Health Sciences Centre published in 1988"
TL;DR: A review of the evidence supporting the belief that caffeine causes arrhythmias is presented in this paper, showing that moderate ingestion of caffeine does not increase the frequency or severity of arrhythmia in normal persons.
39 citations
TL;DR: Thromboxane may stimulate or inhibit lymphatic pumping depending on the concentration of the agent and the transmural pressure applied to the vessel, which may relate to its ability to induce variable changes in luminal diameter and frequency and force of contractions.
23 citations
01 Feb 1988
TL;DR: The observation that many patients with FH F now die of complications of increased intracranial pressure (ICP), which accounted for 9 of the 14 deaths recently observed at this institution, makes it imperative that patients withfulminant hepatic failure be carefully monitored for signs of increased ICP and that appropriate therapy be instituted.
Abstract: Fulminant hepatic failure (FHF) is the acute failure of liver function occurring in a patient with no antecedent liver disease and in whom hepatic encephalopathy supervenes within 8 weeks after the onset of clinical symptoms. The syndrome of FH F remains among the most challenging and difficult problems encountered by clinicians. Although some controversy exists about the management of this syndrome, the development of new and sophisticated intensive care unit monitoring equipment and treatment modalities has likely resulted in improved survival among patients with FHF. The rate of survival from FH F in patients with stage 4 hepatic encephalopathy (hepatic coma) treated with supportive care in a liver unit in 1987 was probably approximately 20 to 35%. In a personal series of 21 patients managed during the past 2 years, before the performance of orthotopic liver transplantation for FHF, 7 patients survived with good supportive care alone. Although this result may indeed be an improvement in comparison with earlier survival figures of 10 to 20% reported more than a decade ago, 1 the poor prognosis still underscores the need for a better understanding of the pathophysiologic aspects of the complications associated with FHF and their treatment. In particular, the observation that many patients with FH F now die of complications of increased intracranial pressure (ICP), which accounted for 9 of the 14 deaths recently observed at our institution, makes it imperative that patients with FHF be carefully monitored for signs of increased ICP and that appropriate therapy be instituted. 2 Naturally, some investigators have expressed opposition to the routine placement of ICP monitors in patients with FH F because of their coagulopathy and risk for infection. In the few centers
22 citations
TL;DR: Practical considerations in answering consultation requests are discussed with respect to "hidden agendas" of the consultee, role and expectations of the psychiatrist, and problem referrals.
Abstract: As Consultation-Liaison Services continue to develop and expand in general hospitals, psychiatrists must be aware of pitfalls and pratfalls inherent in dealing with medical colleagues and other allied health professionals, as well as with the patients. Practical considerations in answering consultation requests are discussed with respect to "hidden agendas" of the consultee, role and expectations of the psychiatrist, and problem referrals. It is only through mutual respect and collaboration that Consultation-Liaison Services can truly be effective.
1 citations