Showing papers by "University of Arkansas for Medical Sciences published in 1970"
TL;DR: Although dehydration of the aqueous humor and lens is the most important factor in development of the lens transparency change, there are other factors which also play a role and this group of cataracts can be classified into a single group with common characteristics.
60 citations
TL;DR: Evidence in support of the proposed mechanism includes consideration of the structure and degradation of thyroxin, the ability of iodine to exhibit thyromimetic actions, the interaction of iodine with phospholipid model membranes resulting in decreased electrical resistance of the membranes, and the abilityof iodine to lower the activation energy for electrical conduction in lipids in the solid state.
21 citations
Journal Article•
TL;DR: In the hamster's galactose cataract, the increase in dulcitol and increase in water were closely related but not exactly parallel, so the cataracts were partially reversible.
Abstract: The rat has been the only laboratory animal in which galactose cataracts have been •produced in vivo. Syrian golden hamsters, when fed a diet of 45 to 85 per cent galactose, also develop cataracts. With increasing concentrations of galactose, weight loss and death frequently occurred. The b'.omicroscopic lens changes were similar to those reported in the rat, and the cataracts were partially reversible. The data showed a quadratic relationship between didcitol accumulation and (1) days on the galactose diet with a 98 per cent degree of fit and (2) stage of cataract formation loith a 79 per cent degree of fit. A linear relationship was demonstrated when the water content was compared with (1) days on the galactose diet with a 77 per cent degree of fit and (2) stage of cataract formation with a 71 per cent degree of fit. Therefore, in the hamster's galactose cataract, the increase in dulcitol and increase in water were closely related but not exactly parallel.
1 citations