ACS Applied Nano Materials 

About: ACS Applied Nano Materials is an academic journal published by American Chemical Society. The journal publishes majorly in the area(s): Chemistry & Engineering. It has an ISSN identifier of 2574-0970. Over the lifetime, 2909 publications have been published receiving 7125 citations. The journal is also known as: Applied nano materials & American Chemical Society applied nano materials.

Synergistic Effects Between Metal Nanoparticles and Commercial Antimicrobial Agents: A Review

Abstract: Nanotechnology has expanded into a broad range of clinical applications. In particular, metal nanoparticles (MNPs) display unique antimicrobial properties, a fundamental function of novel medical devices. The combination of MNPs with commercial antimicrobial drugs (e.g., antibiotics, antifungals, and antivirals) may offer several opportunities to overcome some disadvantages of their individual use and enhance effectiveness. MNP conjugates display multiple advantages. As drug delivery systems, the conjugates can extend the circulation of the drugs in the body, facilitate intercellular targeting, improve drug stabilization, and possess superior delivery. Concomitantly, they reduce the required drug dose, minimize toxicity, and broaden the antimicrobial spectrum. In this work, the common strategies to combine MNPs with clinically used antimicrobial agents are underscored. Furthermore, a comprehensive survey about synergistic antimicrobial effects, the mechanism of action, and cytotoxicity is depicted.