Showing papers in "American Journal of Obstetrics and Gynecology in 2022"

TL;DR: In this article , the authors investigated the uptake and safety of COVID-19 vaccination among pregnant women and found that vaccination was not significantly associated with birth at <40 weeks' gestation (hazard ratio 0.93; 95% confidence interval, 0.71 and 1.079).

TL;DR: In this paper , the authors found that pregnant persons were more likely to be admitted to an intensive care unit, require invasive ventilation, require extracorporeal membrane oxygenation, and die than nonpregnant women of reproductive age.

TL;DR: In this paper , the authors examined the relationship between SARS-CoV-2 infection during pregnancy and the risk for preeclampsia and reported unadjusted and/or adjusted risk estimates and 95% confidence intervals or data to calculate them.

TL;DR: In this paper , the authors present a review of the existing literature on the different methods, recommendations by professional organizations, quality assessment of different components of risk assessment, and clinical implementation of the first trimester screening for preeclampsia.

TL;DR: In this paper , the authors evaluated the changes in care and short-term outcomes of surgical patients with gynecologic cancers during the COVID-19 pandemic, and they hypothesized that the delay in surgical cancer care, especially in patients who required more extensive surgery, and such delay had an impact on cancer outcomes.

TL;DR: A review of the current knowledge of spiral artery remodeling defects and acute atherosis in preeclampsia can be found in this paper , where the authors also discuss the role of acute atrorosis in the pathophysiology of preeclampia and short and long-term health correlates.

TL;DR: In this paper , Syncytiotrophoblast stages of early and late-onset preeclampsia share a common feature that causes the maternal syndrome, which is the most relevant feature for preeclampia.

TL;DR: In this paper , the potential etiologies of preeclampsia are reviewed along with the potential mechanisms involved, such as the breakdown of maternal-fetal immune tolerance (thought to account for the excess of preterm labor in primipaternity and egg donation), whereas other factors such as placental aging may operate largely through syncytiotrophoblast stress.

TL;DR: The Aspirin for Evidence-Based Preeclampsia Prevention trial as discussed by the authors showed that aspirin at a daily dosage of 150 mg, initiated before 16 weeks of gestational age, and given at night to a high-risk population, identified by a combined first trimester screening test, reduced the incidence of preterm preeclampia by 62%.

TL;DR: The message of "eat better, not more" can be achieved by basing diet on a variety of nutrient-dense, whole foods, including fruits, vegetables, legumes, whole grains, healthy fats with omega-3 fatty acids that include nuts and seeds, and fish, in place of poorer quality highly processed foods as discussed by the authors .

TL;DR: In this paper , the authors used angiogenic biomarkers to diagnose preeclampsia and related disorders of placentation, such as intrauterine growth restriction and twin-to-twin transfusion syndrome, and fetal hydrops.

TL;DR: In this article , the trends of illness severity among obstetrical patients with COVID-19, on a background of Delta variant predominance, were reported and described in this cohort at Parkland Hospital.

TL;DR: Preeclampsia is a disease whose characterization has not changed in the 150 years since the cluster of signs associated with the disorder were first described as mentioned in this paper , however, there is still little consensus regarding the true etiology of preeclampia.

TL;DR: For example, Baik et al. as discussed by the authors found that SARS-CoV-2 infection, COVID-19 vaccination, and/or psychological stress related to the CoV-19 pandemic may influence the menstrual cycle.

TL;DR: The role of race and ethnicity in the burden of preeclampsia is examined in this paper , where a multilevel framework is proposed to take into account the influence of behavioral factors, environmental factors, and healthcare systems, not just on the individual.

TL;DR: Grossman et al. as mentioned in this paper report the experiences from two urban, inner-city healthcare systems in Texas after state-level legislation on abortion has encroached on access to reproductive care with disproportionate effects on underserved communities.

TL;DR: A summary of available evidence provides data and expert opinion on possible pathogenesis of eclampsia, imaging findings, differential diagnosis, and stepwise approach regarding the management of ECLampsia before delivery and after delivery as well as current recommendations for the prevention of Eclamptic seizures as mentioned in this paper .

TL;DR: The release of antiangiogenic factors by the placenta is viewed as an adaptive response to improve uterine perfusion by modulating endothelial function and maternal cardiovascular performance, which can become maladaptive and lead to damage of target organs during pregnancy or the postpartum period.

TL;DR: In this article , a review of pregnancy hypertension clinical practice guidelines to inform international clinical practice and research priorities is presented. But the authors focus on the use of dipstick proteinuria testing for screening followed by quantitative testing by urinary protein-to-creatinine ratio or 24-hour urine collection.

TL;DR: In this paper , the authors found that sexual intercourse increases the number of dendritic cells in the uterus that play an important role in the induction of paternal antigen-specific regulatory T cells.

TL;DR: In this article , the impact of monkeypox infection on maternal, fetal, and neonatal health is discussed, including the risks of heart rate-corrected QT-interval prolongation, inaccuracies in blood glucose monitoring, and the predisposition to iatrogenic venous thromboembolism.

TL;DR: In this article , a review of the existing literature on preeclampsia can be found in Section 5.1.1, where the authors delineate the physiological hemodynamic changes that occur in normal pregnancy and those that are observed with the pathologic processes associated with preeclampia.

TL;DR: A review of the literature about the diagnosis, antepartum surveillance, and time of delivery of fetuses suspected to be small for gestational age or growth restricted is presented in this article .

TL;DR: The placenta is a highly metabolically active organ fulfilling the bioenergetic and biosynthetic needs to support its own rapid growth and that of the fetus as discussed by the authors , but its causal relationship to the pathophysiology is unclear.

TL;DR: In this article , the authors show that immunization against COVID-19 with an mRNA vaccine is safe for pregnant people, emphasizing that the potential maternal and fetal benefits of vaccination greatly outweigh the potential risks of vaccination.

TL;DR: In this paper , the performance of single-nucleotide polymorphism-based, prenatal cell-free DNA screening for detection of 22q11.2 deletion syndrome was evaluated with blinding to the pregnancy outcome.

TL;DR: In this paper , the authors proposed that the most important factor that influences maternal and neonatal outcome is the severity of blood pressures and presence of end organ damage, rather than the excess protein excretion.

TL;DR: In this article , the authors used generalized linear models with a Poisson distribution and log link function, with robust standard errors to account for model misspecification, to determine whether diabetes mellitus and high body mass index are risk factors for COVID-19 in pregnancy.

TL;DR: This article performed a meta-analysis on the risk factors for primary pelvic organ prolapse and prolapse recurrence and found that parity, parity, birthweight, age, body mass index, levator defect, and levator hiatal area are risk factors, and cesarean delivery and smoking are protective factors.

TL;DR: In this article , the performance of cell-free DNA noninvasive prenatal screening for trisomies 21, 18, and 13 between women at a low and high risk for aneuploidy in a large, prospective cohort with genetic confirmation of results was compared.