Journal•ISSN: 1363-1950
Current Opinion in Clinical Nutrition and Metabolic Care
Lippincott Williams & Wilkins
About: Current Opinion in Clinical Nutrition and Metabolic Care is an academic journal published by Lippincott Williams & Wilkins. The journal publishes majorly in the area(s): Medicine & Parenteral nutrition. It has an ISSN identifier of 1363-1950. Over the lifetime, 2297 publications have been published receiving 110673 citations. The journal is also known as: Curr Opin Clin Nutr Metab Care & Current opinion in clinical nutrition & metabolic care.
Papers published on a yearly basis
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TL;DR: It is proposed that the risk of adverse outcomes, such as functional limitation and mortality, is better estimated by considering jointly obesity and muscle strength rather than Obesity and muscle mass and the term ‘sarcopenic obesity’ should be revisited.
Abstract: Purpose of the review
Older obese persons with decreased muscle mass or strength are at special risk for adverse outcomes. We discuss potential pathways to muscle impairment in obese individuals and the consequences that joint obesity and muscle impairment may have on health and disability. Tantamount to this discussion is whether low muscle mass or, rather, muscle weakness should be used for the definition.
899 citations
TL;DR: Systemic inflammation-based prognostic scores not only identify patients at risk but also provide well defined therapeutic targets for future clinical trials targeting nutritional decline.
Abstract: Purpose of reviewThere is now good evidence in humans that a chronic systemic inflammatory response results in the cardinal features of cancer cachexia, principally the progressive loss of weight (in particular lean tissue). This review examines the role of recent simple objective systemic inflammat
793 citations
TL;DR: Clinicians should stress the importance of ingesting a sufficient amount of protein with each meal to preserve skeletal muscle mass in ageing and propose a novel and specific dietary approach to prevent or slow down muscle loss with ageing.
Abstract: Purpose of review Summary On the basis of recent work, we propose a novel and specific dietary approach to prevent or slow-muscle loss with ageing. Rather than recommending a large, global increase in the recommended dietary allowance (RDA) for protein for all elderly individuals, clinicians should stress the importance of ingesting a sufficient amount of protein with each meal. To maximize muscle protein synthesis while being cognizant of total energy intake, we propose a dietary plan that includes 25-30g of high quality protein per meal.
746 citations
TL;DR: There is an ongoing need to perfect methods that provide information beyond mass and structure (static measures) to kinetic measures that yield information on metabolic and biological functions.
Abstract: Purpose of reviewThe present study reviews the most recently developed and commonly used methods for the determination of human body composition in vivo with relevance for nutritional assessment.Recent findingsBody composition measurement methods are continuously being perfected with the most common
601 citations
TL;DR: There is abundant evidence that the proportion of energy derived from fat during exercise is higher in women than in men, and this finding seems counterintuitive, as percentage body fat is increased in women.
Abstract: Women generally have a higher percentage of body fat than men. Also, women store more fat in the gluteal-femoral region, whereas men store more fat in the visceral (abdominal) depot. This review focuses on differences in regional fatty acid storage, mobilization and oxidation that may contribute to gender-related differences in body fat distribution. There are pronounced regional differences in the regulation of regional fatty acid metabolism between men and women. Firstly, there is evidence that in vivo, catecholamine mediated leg free fatty acid release is lower in women than in men, whereas free fatty acid release from the upper body depots is comparable. These data correspond to in-vitro adipose tissue biopsy data, which indicate a more pronounced difference in catecholamine mediated lipolysis between upper body and lower body fat depots in women than in men. Secondly, free fatty acid release by the upper body subcutaneous fat depots is higher in men than in women, indicating a higher resistance to the antilipolytic effect of meal ingestion in the upper body fat depots in men. Thirdly, there are indications that basal fat oxidation (adjusted for fat free mass) is lower in females as compared to males, thereby contributing to a higher fat storage in women. Finally, postprandial fat storage may be higher in subcutaneous adipose tissue in women than in men, whereas storage in visceral adipose tissue has been hypothesized to be higher in men. All the above differences may play a role in the variation in net regional fat storage between men and women, but the number of in-vivo studies on gender-related differences in fatty acid metabolism is very limited and most findings require confirmation. Furthermore, there is abundant evidence that the proportion of energy derived from fat during exercise is higher in women than in men. With respect to total body fat, this finding seems counterintuitive, as percentage body fat is increased in women. Further studies are necessary to investigate the significance of differences in exercise-induced fat oxidation on 24-h fat balance.
579 citations