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Showing papers in "Health science reports in 2022"


Journal ArticleDOI
TL;DR: This systematic review aimed to systematically review the studies addressing this issue worldwide of the impacts of the COVID‐19 pandemic on vaccination coverage in children and adolescents.
Abstract: Scientists and healthcare workers have expressed their concerns on the impacts of the COVID‐19 pandemic on vaccination coverage in children and adolescents. Therefore, we aimed to systematically review the studies addressing this issue worldwide.

55 citations


Journal ArticleDOI
TL;DR: In this article , the authors aimed to systematically review the mortality in coronavirus disease 2019 (COVID•19) patients and its predictors in this age group and found that older people have higher rates of comorbidities and may experience more severe inflammatory responses; therefore, are at higher risk of death.
Abstract: Older people have higher rates of comorbidities and may experience more severe inflammatory responses; therefore, are at higher risk of death. Herein, we aimed to systematically review the mortality in coronavirus disease 2019 (COVID‐19) patients and its predictors in this age group.

50 citations


Journal ArticleDOI
TL;DR: This rapid review and discussed the repurposing potentials of smallpox vaccines and drugs in monkeypox infection based on their comparative benefits and risks.
Abstract: There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on their comparative benefits and risks. Therefore, we conducted this rapid review and discussed the repurposing potentials of smallpox vaccines and drugs in monkeypox infection.

33 citations


Journal ArticleDOI
TL;DR: A comparative evaluation of authorized drugs for treating Covid‐19 patients and the antiviral drugs provide a new tool to fight the Covid-19 pandemic.
Abstract: Vaccines are the first line of defense against coronavirus disease 2019 (Covid‐19). However, the antiviral drugs provide a new tool to fight the Covid‐19 pandemic. Here we aimed for a comparative evaluation of authorized drugs for treating Covid‐19 patients.

28 citations


Journal ArticleDOI
TL;DR: There is enough evidence to conclude that the COVID‐19 pandemic has impacted the efforts being taken to prevent outbreaks of RVF, and with no definitive treatment in place and inadequate preventive measures and disease control, RVF may potentially lead to a future epidemic unless addressed urgently.
Abstract: A new rising incidence of Rift Valley fever (RVF) among livestock and humans in the African continent during the COVID‐19 pandemic has become of increasing concern. We analyzed the different ways COVID‐19 has contributed to the increase in RVF cases and how it has impacted the interventions allocated to the disease by comparing it with the status of the disease before the pandemic. There is enough evidence to conclude that the COVID‐19 pandemic has impacted the efforts being taken to prevent outbreaks of RVF. Therefore, with no definitive treatment in place and inadequate preventive measures and disease control, RVF may potentially lead to a future epidemic unless addressed urgently.

26 citations


Journal ArticleDOI
TL;DR: This study evaluates the prevalence and severity of depression, anxiety, stress, and perceived stress and their relation with resilience associated with the COVID‐19 pandemic among a sample of the general population in Southern Iran.
Abstract: Home quarantine and physical distancing at the time of coronavirus disease 2019 (COVID‐19) had a severe effect on the mental health of the populations. Resilience has been reported previously to be a protective factor against anxiety, stress, and depression. This study evaluates the prevalence and severity of depression, anxiety, stress, and perceived stress and their relation with resilience associated with the COVID‐19 pandemic among a sample of the general population in Southern Iran.

23 citations


Journal ArticleDOI
TL;DR: Mulormycosis and COVID‐19 co‐infection might adversely affect patients' outcomes, and the related evidence and the subsequent outcomes are reviewed.
Abstract: Several reports previously described mucormycosis co‐infection in patients with COVID‐19. As mucormycosis and COVID‐19 co‐infection might adversely affect patients' outcomes, we aimed to systematically review the related evidence and the subsequent outcomes.

19 citations


Journal ArticleDOI
TL;DR: The newly emerged variant has arrived in Europe during the devastating fourth wave of COVID‐19 upsurge due to the Delta variant, and two doses of AstraZeneca's nCoV‐19 or BioNTech's BNT162b2 vaccines are effective against symptomatic infection.
Abstract: The latest variant named SARS‐CoV‐2 Omicron (B.1.1.529) is the most heavily muted strain discovered so far in one of the provinces in South Africa on November 24, 2021. TheWorld Health Organization (WHO) has designated the newly detected variant as Variant of Concern (VOC) on November 26, 2021. After Alpha, Beta, Gamma, and Delta, it is the fifth VOC of coronavirus. The distinguishing characteristic of Omicron is the prime immunogenic target of antibodies triggered by immunization or through natural infections, which can hold an astonishingly huge number of genetic alterations (more than 50), of which nearly 30 mutations are on the spike (S) membrane protein, most likely to aggregate around the site of receptor‐binding motif; the consensus sequence of this variant has 44 amino acid changes, deletion of 6 amino acids, and insertion of 1 amino acid when compared with the reference strain of SARS‐CoV‐2. Europe has become the epicenter of the COVID‐19 pandemic again due to the re‐emergence of COVID‐19 cases in European countries. According toWHO, the highly contagious Delta variant has just two mutations to the receptor‐binding domain that accounts for more than 99% of COVID‐19 infections of theWorld before the introduction of Omicron. Following South Africa, more than 150 countries have been detected with Omicron variant as of January 20, 2022, and the United Kingdom reported the first known death of a patient with Omicron variant. The newly emerged variant has arrived in Europe during the devastating fourth wave of COVID‐19 upsurge due to the Delta variant. As of January 28, 2022, Europe logged more than 138 million COVID‐19 cases, which is the highest across the region followed by the Americas (more than 132 million confirmed cases). Also, Europe is currently representing 38% of all COVID‐19 cases reported globally. In Europe, people gather together in the run‐up to the religious festival Christmas during the early winter season; this is when the new variant Omicron had arrived, hence this season might have provided a perfect ground for mass transmission of the virus. The COVID‐19 symptoms due to the Omicron variant are milder so far. However, the Omicron variant could potentially raise death rates due to its very high transmissibility. People suffer flu‐like symptoms due to the Omicron variant. The major symptoms for the Omicron variant are fever, sore throat, cough, weariness, and aches, whereas low oxygen saturation, abnormal pulse rates, and shortness of breath are frequently reported symptoms for the Delta variant. Moreover, tiredness, sore throat, muscle or body aches, loss of taste or smell, runny nose were common for earlier variants. We do not have enough epidemiological data about the Omicron variant yet. However, some early studies suggest that the illness due to the Omicron variant is mild so far. The findings by research in England, Scotland, and South Africa stated that the omicron variation has a 15%−80% reduced risk of hospitalization than the Delta variant. Approximately, 15%−20% infected individuals with the Omicron variant may require to visit the hospital, which is a 40%−45% lower probability of hospitalization than those infected with the Delta variant. According to new data from South Africa, during October and November of 2021, Omicron infection shows an 80% lower count in people with other variants having a lesser likelihood of being admitted to the hospital. According to preliminary data by the Health Security Agency of the United Kingdom, two doses of AstraZeneca's nCoV‐19 or BioNTech's BNT162b2 vaccines are effective against symptomatic infection. However, the increased rate of infections among the people who were previously infected or have received double vaccine shots has created new worries across the countries. Pfizer and BioNTech reported that three doses of their vaccine are capable of eliminating the new Omicron variant in certain lab tests, and additional booster doses will provide additional protection. A recent Pfizer research claimed that vaccination protection after 6 months dropped from 96.2% to 83.7%. According to their findings, the Pfizer (two doses) vaccine provides more than 80% immunity against severe illness and death, while additional boosters might increase the immunity by 10%. Moreover, US‐FDA authorized three antiviral drugs for emergency use in treating COVID‐19 patients. Remdesivir is a nucleotide that inhibits the RNA‐ dependent polymerase enzyme of SARs, which is present in the epithelial cells of the airways in humans; it shows significant nanomolar action. Moreover, molnupiravir shows synergistic effects with other antivirals according to preclinical studies. Also, paxlovid reduces hospitalization or death rate by 89% among

18 citations


Journal ArticleDOI
TL;DR: This systematic review focused on the possible complications of COVID‐19 infection in the fetus and newborn babies including the possibility and evidence of vertical transmission by reviewing articles published during the first year of the CO VID‐19 pandemic.
Abstract: The outbreak of coronavirus disease 2019 (COVID‐19) over the past year has affected public health worldwide. During pregnancy, the maternal immune system and inflammatory responses are widely suppressed. Pregnancy‐related immune system suppression could make the mother vulnerable to infectious diseases like SARS‐COV‐2. However, current data suggest little to no possibility of COVID‐19 transmission in pregnant women to the fetus during pregnancy or childbirth. This systematic review focused on the possible complications of COVID‐19 infection in the fetus and newborn babies including the possibility and evidence of vertical transmission by reviewing articles published during the first year of the COVID‐19 pandemic.

14 citations


Journal ArticleDOI
TL;DR: The aim of this study was to review the mental health status of dentists during COVID‐19 pandemic to assess the impact of coronavirus disease‐2019 on the mental Health Status of Dentists.
Abstract: The effect of coronavirus disease‐2019 (COVID‐19) on the mental health status of dentists has been studied in various studies. The aim of this study was to review the mental health status of dentists during COVID‐19 pandemic.

12 citations


Journal ArticleDOI
TL;DR: The purpose of the current study is to identify the applications and capability of IoT and digital health in the management of the COVID‐19 pandemic.
Abstract: The use of new technologies such as the Internet of Things (IoT) in the management of chronic diseases, especially in the COVID pandemics, could be a life‐saving appliance for public health practice. The purpose of the current study is to identify the applications and capability of IoT and digital health in the management of the COVID‐19 pandemic.

Journal ArticleDOI
TL;DR: In this article , the authors proposed that because of the high implementation costs, it is not possible yet to adopt telehealth systems for low and middle-income nations, and they proposed a solution to solve the problem.
Abstract: Telemedicine offers the possibility of provision of medical assistance to remote patients, and it has great potential in developing countries like Pakistan. Telemedicine solves logistical barriers, gives support to weak health systems, and helps to establish worldwide networks of healthcare professionals. Because of the high implementation costs, it is not possible yet to adopt telehealth systems for low‐ and middle‐income nations.

Journal ArticleDOI
TL;DR: This article aims to present an update on Omicron BA.4 and BA.5 subvariants of SARS‐CoV‐2 and their potential impact on global public health, and recommends prioritized monitoring of epidemiology of the COVID‐19 pandemic due to Omicrons BA.2.
Abstract: A cluster of pneumonia cases was reported by the Wuhan Municipal Health Commission, China, Hubei Province, resulting in the identification of a novel coronavirus (SARS‐CoV‐2). As of September 19, 2022, more than 609 million cases and 6.5 million deaths have been recorded worldwide. The highest number of COVID‐19 cases have been recorded in Europe, followed by the Americas, Western Pacific, South‐East Asia, Eastern Mediterranean, and Africa regions. As a country, the US contributed the highest number of COVID‐19 cases and deaths. SARS‐CoV‐2 is constantly mutating and dodging antibodies to infect more people. Epidemiologists in South Africa detected the fifth and the latest “variant of concern” (VOC) of SARS‐CoV‐2. They reported this new variant to the World Health Organization (WHO) on November 24, 2021. This fifth VOC of SARS‐CoV‐2 contains more than 30 mutations in its viral spike proteins to allow it more transmissibility and infection rates. The WHO named this fifth VOC of SARS‐CoV‐2 as the Omicron variant (B.1.1.529) on November 26, 2021. Omicron became the leading variant in COVID‐19 after its inception. At present, Omicron is the only circulating VOC. Initially, Omicron had three subvariants (e.g., BA.1, BA.2, and BA.3). BA.1 was predominant during the fourth wave of the pandemic in South Africa. However, the global pattern was inconsistent in some other countries. BA.2 variant was responsible for hospitalizations and deaths in most cases during the Omicron wave in South Africa. Currently, the Omicron variant includes five lineages and some other descendant subvariants. Omicron subvariants that have rapidly spread across the globe. Initially, BA.1 and BA.2 were predominant Omicron subvariant worldwide. However, BA.4 and BA.5 variants are now leading in Europe and the United States. The WHO classified BA.4, BA.5, BA.2.12.1, and BA.2.75 as VOC‐subvariants under monitoring. The European Centre for Disease Prevention and Control categorized BA.4 and BA.5 as VOC from VOI on May 12, 2022. Therefore, we recommend prioritized monitoring of epidemiology of the COVID‐19 pandemic due to Omicron BA.4 and BA.5 subvariants. This article aims to present an update on Omicron BA.4 and BA.5 subvariants of SARS‐CoV‐2 and their potential impact on global public health. Scientists detected the BA.4 and BA.5 variants from a sample collected from South Africa in early 2022. BA.4 and BA.5 have similarities with parent variants based on their genotype and phenotype as both are subvariants of Omicron. These subvariants have all mutations that Omicron had. The spike proteins of the latest Omicron BA.4 and BA.5 subvariants are identical and more similar to BA.2 than BA.1. The Omicron BA.4 and BA.5 subvariants fueled a surge of cases in South Africa in the spring despite having widespread pre‐existing immunity to the virus. The COVID‐19 wave due to BA.4 and BA.5 subvariants was not as high as earlier waves, and deaths did not rise as sharply in South Africa.

Journal ArticleDOI
TL;DR: Assessment of fear and depressive symptoms among private job holders in Bangladesh during the Covid‐19 pandemic and associated risk factors is aimed.
Abstract: The ongoing public health emergency has created incredible fear of getting the infection and a terrible psychological burden among all levels. The pandemic has severely affected private job holders' economic status and lifestyle factors in Bangladesh. Here we aimed to assess fear and depressive symptoms among private job holders in Bangladesh during the Covid‐19 pandemic and associated risk factors.

Journal ArticleDOI
TL;DR: The mechanism of cardiac injury is not well defined but, it can be due to direct myocardial infection, respiratory failure or hypoxemia, and indirect injury from systemic inflammatory response separately or all three factors together.
Abstract: The outbreak of Covid‐19 is a real threat to public health. It causes cardiovascular complications such as acute myocardial injury and myocarditis. Symptoms of myocarditis vary from chest pain, tachycardia, or chest tightness. Inotropes and/or vasopressors and mechanical ventilation are the protocols for cardiogenic shock in patients with myocarditis. Some previous studies stated that the mechanism of cardiac injury is not well defined but, it can be due to direct myocardial infection, respiratory failure or hypoxemia, and indirect injury from systemic inflammatory response separately or all three factors together. The pathologic processes included direct myocardial injury by virus binding to ACE2, systemic inflammation, altered myocardial demand‐supply ratio, and plaque and coronary thrombosis. There are disagreements on the usage of corticosteroids in active‐infection myocarditis. As everyday new complications of Covid‐19 appear, there is a need for further research to overcome them.

Journal ArticleDOI
TL;DR: Investigation of the one‐year changes in the prevalence and correlates of depressive symptoms during the COVID‐19 pandemic among medical science students in Iran indicated that depression mean score was significantly higher in post outbreak assessment, and spiritual well‐being and life satisfaction as positive psychology constructs were recognized as protective factors against depression.
Abstract: The COVID‐19 pandemic has imposed a significant psychological burden on many across society especially students studying medical sciences. This study intended to investigate the one‐year changes in the prevalence and correlates of depressive symptoms during the COVID‐19 pandemic among medical science students.

Journal ArticleDOI
TL;DR: One of the known risk factors for hypertensive crisis (HTN‐C) is non‐steroidal anti‐inflammatory drugs (NSAIDs) which their adverse effects can lead to end‐organ damage such as gastrointestinal and cardiovascular issues.
Abstract: One of the known risk factors for hypertensive crisis (HTN‐C) is non‐steroidal anti‐inflammatory drugs (NSAIDs) which their adverse effects can lead to end‐organ damage such as gastrointestinal and cardiovascular issues.

Journal ArticleDOI
TL;DR: This study aimed to measure the prevalence rate and predicting factors for depression, anxiety and stress, suicidal ideation, and suicide attempts in Bangladeshi undergraduate rehabilitation students.
Abstract: Common mental health symptoms (CMHS) like depressive moods, anxiety, and stress are the underlying causes of suicidal behavior. The incidence of suicide is higher among Bangladeshi students. Due to the pandemic, students of health/rehabilitation sciences are at the most significant risk. This study aimed to measure the prevalence rate and predicting factors for depression, anxiety and stress, suicidal ideation, and suicide attempts in Bangladeshi undergraduate rehabilitation students.

Journal ArticleDOI
TL;DR: It is vital to summarize the clinical characteristics of COVID‐19 patients and to investigate the risk factors linked to CO VID‐19 severity in Sudanese patients.
Abstract: Since December 2019, (COVID‐19) has had a significant impact on global health systems. Because little is known about the clinical characteristics and risk factors connected with COVID‐19 severity in Sudanese patients, it is vital to summarize the clinical characteristics of COVID‐19 patients and to investigate the risk factors linked to COVID‐19 severity.

Journal ArticleDOI
TL;DR: In 2018, three MPXV cases were detected in the United Kingdom, Israel, and Singapore for the first time, demonstrating that the virus was exported from Nigeria to countries other than its endemic regions as discussed by the authors .
Abstract: A zoonosis known as monkeypox (MPX) is brought on by the monkeypox virus (MPXV), a kind of Orthopoxvirus similar to the smallpox virus, a member of the Poxviridae family. The MPXV was initially identified in 1958 at a laboratory in Copenhagen, Denmark, had an epidemic of a pox‐like illness among monkeys. A newborn baby aged 9 months was the first human MPX case identified in 1970 in the Democratic Republic of the Congo (DRC). Then, six MPX confirmed cases were identified until May 1971 in West African nations. Since then, the virus has been verified in thousands of humans across 15 different nations. The first epidemic beyond the African nations was seen in the United States in 2003 after the importation of infected animals from Ghana. Since MPX re‐emerged in Nigeria in 2017, a few individuals affected with MPXV have been reported outside Africa among people who have recently traveled to Nigeria or contacted people visiting Nigeria. In 2018, three MPX cases were detected in the United Kingdom, Israel, and Singapore for the first time, demonstrating that the virus was exported from Nigeria to countries other than its endemic regions. In 2021, two people affected by MPXV were detected in the United States among travelers from Nigeria, one in Maryland and the other in Texas. In the central, northwestern, and southwestern parts of Africa, 25 suspected individuals were identified on February 17, 2022, along with three verified cases and two fatalities. On March 14, 2022, six MPXV cases with two fatalities were reported from the Central African Republic. From the first day of 2022 to mid‐April 2022, throughout 14 territories of DRC, about 1,152 MPX probable cases were recorded in 54 health centers, including 55 fatalities with a mortality rate of 4.8%. From the first day of 2022 to April 30, 2022, Nigeria reported 46 probable cases of MPX, including 15 confirmed cases. The European region recorded the highest confirmed cases of MPX. Two types of MPXV circulate in endemic areas—the Central African (Congo Basin) clade and the West African clade; the latter causes less severe disease and mortality. 2 | THE GLOBAL PUBLIC HEALTH THREAT

Journal ArticleDOI
TL;DR: Evaluated the sleep quality of AA patients, a nonscarring hair loss with autoimmune pathophysiology, which is associated with psychiatric disorders including anxiety and depression, is evaluated.
Abstract: Alopecia areata (AA) is a nonscarring hair loss with autoimmune pathophysiology, which is associated with psychiatric disorders including anxiety and depression. Sleep disorders are commonly seen with anxiety and depression. Here we evaluate the sleep quality of AA patients.

Journal ArticleDOI
TL;DR: This study aimed to identify the factors determining better preventive practices of HCWs toward COVID‐19, the ongoing coronavirus disease 2019.
Abstract: Identifying the factors influencing the preventive practices of the healthcare workers (HCWs) is crucial during the ongoing coronavirus disease 2019 (COVID‐19) because the HCWs are exposed to unparalleled levels of risks. Such concern is starting to be explored worldwide although there is only a single study available in Bangladesh with a limited scope of explorations of the domain. Therefore, this study aimed to identify the factors determining better preventive practices of HCWs toward COVID‐19.

Journal ArticleDOI
TL;DR: In this article , the authors defined among the biomarkers already identified those which are mostly associated with increased death rate in patients with severe coronavirus disease (COVID-19) in patients.
Abstract: Over 4 million deaths from coronavirus disease (COVID)-19 have been reported in the world. Several biomarkers have been identified that predict disease severity, but there is still a need to identify biomarkers for death risk in severe COVID-19. We aim to define amongst the biomarkers already identified those which are mostly associated with increased death rate in patients with severe COVID-19.In this retrospective study conducted in three public hospitals linked to the Medical School of Ribeirão Preto, Brazil, patients with severe COVID-19 were evaluated regarding biomarkers (neutrophil-to-lymphocyte ratio-NLR, D-dimer, fibrinogen) of death risk, obtained before administration of corticosteroids.Thirty-nine (32.8%) of the 119 patients included (104 [87.4%] on mechanical ventilation) died during hospitalization. Non-survivor group had higher median (range) NLR (12.63 [2.6-115] vs 7.43 [0.43-31.8]; P = .001), D-dimer (2.17 [0.27-20.00] vs 1.57 [0.28-20.00]; P = .03), but lower fibrinogen (631 [353-1078] vs 705 [407-1200]; P = .02). The group with NLR ≥ 10 and D-dimer ≥ 2 μg/mL had a higher death risk than the group with NLR < 10 and D-dimer < 2 μg/mL (OR: 5.39; CI 95%: 1.5-19.42; P = .01).High NLR and D-dimer, especially when combined, are predictors of death risk for patients with severe COVID-19 and should be incorporated into their evaluation.

Journal ArticleDOI
TL;DR: This study investigated whether there is an association between ROX index before starting CPAP and within the first 24 hours of starting it and the outcome measure whether patients were weaned off or failed CPAP.
Abstract: Five percent of patients with COVID-19 develop the critical disease, with one of the complications being acute hypoxemic respiratory failure (AHRF) requiring advanced respiratory support. In April 2020, the British Thoracic Society (BTS) issued guidance for the delivery of continuous positive airway pressure (CPAP) to patients with AHRF as a bridging therapy prior to escalation to the intensive care unit (ICU). This therapy has been shown to benefit patients with AHRF due to COVID-19 in a large multi-center trial RECOVERY-RS, their findings are still awaiting peer review. Evidence is needed on how to safely manage these patients outside of ICU and prevent unnecessary delay of intubation. The use of ROX index (ratio of pulse oximetry/fraction of inspired oxygen to respiratory rate) was validated in 2019 to predict whether patients with AHRF can be safely managed on HFNO or if invasive mechanical ventilation (IMV) should be considered. ROX index has also been studied in patients with COVID-19 on HFNO and higher values were found to be associated with HFNO success. This study investigated whether there is an association between ROX index before starting CPAP and within the first 24 hours of starting it and our outcome measure whether patients were weaned off or failed CPAP. Failure was defined as either death or needing IMV depending on their treatment escalation plan.

Journal ArticleDOI
TL;DR: In this paper , the authors evaluated whether hemogram-derived ratios could predict in-hospital deaths in COVID•19 patients, and found that they could be used to predict mortality in a large number of patients.
Abstract: To address the problem of resource limitation, biomarkers having a potential for mortality prediction are urgently required. This study was designed to evaluate whether hemogram‐derived ratios could predict in‐hospital deaths in COVID‐19 patients.

Journal ArticleDOI
TL;DR: Patients on maintenance dialysis are a high‐risk, immune‐compromised population with 15%–25% coronavirus disease (COVID‐19) mortality rate that has been underrepresented in CO VID‐19 vaccination clinical trials.
Abstract: Patients on maintenance dialysis are a high‐risk, immune‐compromised population with 15%–25% coronavirus disease (COVID‐19) mortality rate that has been underrepresented in COVID‐19 vaccination clinical trials. The aim of study was to review of those studies to determine the safety and efficacy of the COVID‐19 vaccination in chronic kidney disease (CKD) patients receiving maintenance hemodialysis systematically.

Journal ArticleDOI
TL;DR: This meta‐analysis addresses whether ciNPT at −125 mmHg or −80‬mmHG or conventional dressing reduces the incidence of surgical site complications in hip and knee arthroplasty.
Abstract: Closed‐incision negative pressure wound therapy (ciNPT) has shown promising effects for managing infected wounds. This meta‐analysis explores the current state of knowledge on ciNPT in orthopedics and addresses whether ciNPT at −125 mmHg or −80 mmHg or conventional dressing reduces the incidence of surgical site complications in hip and knee arthroplasty.

Journal ArticleDOI
TL;DR: Based on available online literature, the authors reviewed the majority of the data representing the outbreak, diagnosis, treatment, and prevention of monkeypox and identified the most important orthopoxvirus for public health.
Abstract: Monkeypox is a viral zoonotic disease caused by the monkeypox virus, a double‐stranded DNA‐enveloped virus that can be transmitted from animal to human or human to human. Consequently, it emerged as the most important orthopoxvirus for public health. Based on available online literature, this study reviewed the majority of the data representing the outbreak, diagnosis, treatment, and prevention of monkeypox.

Journal ArticleDOI
TL;DR: In this paper , the authors aimed to explain the incidence, mortality, and burden of ovarian cancer using the global burden of disease (GBD) 2019 study and found that ovarian cancer has the highest mortality rate among gynecological malignancies and is associated with poor prognosis.
Abstract: Ovarian cancer has the highest mortality rate among gynecological malignancies and is associated with poor prognosis. Since the accurate assessment of the global burden along with the trend of cancers contributes to the development of policies, this study aimed to explain the incidence, mortality, and burden of ovarian cancer using the global burden of disease (GBD) 2019 study.

Journal ArticleDOI
TL;DR: Technologies have been developed to address challenges encountered during wound care with the aim of alleviating pain, promoting healing, or controlling wound infections.
Abstract: Wound treatment comprises a substantial portion of the healthcare budgets in developed countries. Studies suggest that about 50% of patients admitted to hospitals have wounds, while 1%−2% of the general population in the developed world suffers from chronic wounds. Chronic wounds fail to repair themselves within the expected period of 30 days. Technologies have been developed to address challenges encountered during wound care with the aim of alleviating pain, promoting healing, or controlling wound infections.