Journal of hematology 

About: Journal of hematology is an academic journal published by Elmer Press, Inc.. The journal publishes majorly in the area(s): Medicine & Internal medicine. It has an ISSN identifier of 1927-1212. Over the lifetime, 330 publications have been published receiving 1070 citations. The journal is also known as: JH.

Studies in Iron Transportation and Metabolism. Part VI, Absorption of Radioactive Iron in Patients with Fever and with Anemias of Varied Etiology

Abstract: 1. The isotope technic for studying iron absorption has been extended to measure the unabsorbed isotope in feces as well as the amount synthesized into hemoglobin. The recovery of radioiron from feces was shown to be accurate within 10 per cent. 2. There was suggestive evidence to indicate that, with the 1 mg. per kilogram dose employed, normal subjects may sometimes absorb more iron than is converted within a two week period into hemoglobin. 3. Patients with fever, untreated pernicious anemia, and refractory anemia were shown to absorb more iron than they use for hemoglobin. 4. Patients with hemolytic anemia may absorb more iron than can be recovered in the peripheral blood at any one time because isotopic hemoglobin is removed from the circulation at a rapid rate. 5. Except in afebrile patients with hypochromic anemia, acceptance of the per cent of a given dose of radioiron which appears in circulating hemoglobin as a measure of iron absorption must be made with caution. 6. The theory that mucosal cells accept iron for absorption or block its assimilation provides the best known explanation for iron absorption; but patients with adequate iron stores may assimilate considerable quantities of the metal and the block must be regarded as relative.

Plateletcrit as a Screening Tool for Detection of Platelet Quantitative Disorders

Abstract: Background: Context-Plateletcrit is a measure of total platelet mass. Values vary depending on mean platelet volume resulting in overlap between normal platelets, thrombocytopenia and thrombocytosis. Aims of this study were to record platelet indices in our hospital set up and evaluate normal range of plateletcrit which could screen thrombocytopenia, thrombocytosis and normal platelet count. Methods: We studied platelet indices in 206 patients using Advia 2120 analyzer. At seven different cut off ranges of Plateletcrit the sensitivity and specificity for detecting thrombocytopenia and thrombocytosis was calculated. Results: The average of Mean platelet volume was 9.13 fl, plateletcrit- 0.23% and Platelet distribution width-56.6% in normal platelet counts. Sensitivity and specificity for detection of thrombocytopenia at plateletcrit cut off range of 0.20-0.36% is 97 and 80% and 94 and 98% for thrombocytosis. Conclusion: In our hospital set up we found that majority of our patients with normal platelet count have a plateletcrit within the range of 0.20-0.36%. Plateletcrit is an effective screening tool for detecting platelet quantitative abnormalities. doi: http://dx.doi.org/10.4021/jh70w

Prevalence of Anemia in Type 2 Diabetic Patients.

Abstract: Background: The aim of the study was to determine the prevalence of anemia in patients with type 2 diabetes and to assess the risk of anemia according to gender, age and glycemic control. Methods: The study group comprised of patients with type 2 diabetes attending Outpatient Diabetic Department of Amiri Hospital (Al-Asimah Capital area) from January 1, 2016 to December 31, 2017. Patients were divided into groups according to glycemic status and gender. Glycated hemoglobin (HbA1C) values and hemoglobin (Hb) levels were evaluated. The presence of anemia was defined by an Hb level < 13.0 g/dL for men and < 12.0 g/dL for women. Results: The prevalence of anemia is significantly greater in diabetic females (38.5%) than in diabetic males (21.6%) and in poorly controlled diabetics (33.46%) than those with glycemic status under control (27.9%) (P < 0.05). The average age of patients with anemia was found to be 60.69 ± 0.198 years and the average age of patients without anemia was found to be 54.07 ± 0.121 years. This indicates that the risk of anemia increases with age. Conclusion: Screening for anemia at the time of diagnosis of diabetes, diabetic medication compliance, awareness of the risk of anemia and other complications in the diabetic patients helps in reducing the prevalence of anemia in diabetic population. J Hematol. 2018;7(2):57-61 doi: https://doi.org/10.14740/jh411w

Thrombocytopenia in Adults: Review Article

Abstract: Thrombocytopenia is the result of falling the number of platelet from 150,000/mi croL . There are three main reasons of thrombocytopenia, a-Decreasing of making platelet b-Increasing of destruction platelet c-Changing of distribution platelet. Pseudothrombocytopenia must be kept in mind too. Both hereditary and acquired reasons help thrombocytopenia have wide spreaded, but acquired causes are more common with increasing age. Thrombocytopenia separates three stages as numerical. Mild: 100,000 - 150,000/mi croL , Moderate: 50,000 - 100,000/mi croL . Severe: < 50,000/mi croL . However, thrombocytopenia is not usually detected clinically until the platelet count has fallen to levels below 100,000/mi croL . Severe thrombocytopenia, such as intracerebral and intra-abdominal bleeding may be life threatening . So diagnosing the treatment immediately can save the life. Transfusion of platelet may not need in all thrombocytopenias. Treatment of the underlying disease may be sufficient . The reason of thrombocytopenia can be temporary but also can be caused severe diseases. Causes of thrombocytopenia change development levels of countries, according to geographical distribution and application centers. In this review we emphasize common etiologies seen in adult patients with thrombocytopenia. doi:10.4021/jh28w