Showing papers in "Journal of Investigative Dermatology in 1959"

TL;DR: It is of considerable interest to analyze the epidermal lipids as they occur in the Malpighian layer because they may be altered in transit to the surface and may also be diluted by admixture with sebum.

TL;DR: A test of the hypothesis would be to determine whether the histologic and cytologic changes occurring in the epidermis during healing of the lesion of psoriasis are similar following the different therapeutically effective agents.

TL;DR: Some of man's earliest research efforts were concerned with attempts to restore the normal skin color to scattered, pigment-less areas considered to be leprosy, although most of which were probably vitiligo.

TL;DR: No attempt will be made in this communication to discuss the many and varied studies concerned with this problem which have been carried out since Findlay demonstrated that cutaneous cancer could be produced in the skin of mice by repeated exposure to mercury arc radiation.

TL;DR: The involvement of ultraviolet light in the induction of skin cancer has been established in both man and animals as discussed by the authors, and it has been shown that prolonged exposure of albino rats to sunlight would result in a high incidence of tumors in the exposed areas.

TL;DR: This work follows as a natural sequence previous work on blister formation and acantholysis by one of the authors as well as the observations that cantharidin ac antholysis will take place in expiants of human skin incubated in serum at 37° C.

TL;DR: The face is supplied by numerous branches from the external and internal carotid arteries, except for the principal branches, which have a small diameter and only a few of them pass to the facial skin as direct'' or cutaneous arteries.

TL;DR: As the processes of growth, maturation, and senescence make varying demands on the body as a whole, similar demands are placed on the epidermis in the various periods of life while it continues its functions.

TL;DR: The penetration of various anionic surfactants (constituents of soaps and household cleansers) into the different layers of the skin and the factors which affect this penetration are studied.

TL;DR: Cases with lesions occurring as frequently as every two weeks, although often the intervals are greater, are observed, and the temporary disfigurement produced can be a source of considerable distress.

TL;DR: In vitro and in vivo methods are utilized for exploring the factors which influence and regulate the allergic response and the role of immune checkpoints is explored.

TL;DR: In 1894, P. G. Unna observed in discussing the histopathology of tumors that prolonged exposure to sunlight might give rise to malignant tumors of the skin and the role of pigmentation in protecting the skin from actinic rays was recognized.

TL;DR: The therapeutic efficacy of orally administered griseofulvin for the treatment of superficial fungous infections due to dermatophytes seems established and the antibiotic was strikingly effective in curing guinea pigs experimentally infected with Trichophyton mentagrophytes.