•Journal•ISSN: 1420-4096
Kidney & Blood Pressure Research
Karger Publishers
About: Kidney & Blood Pressure Research is an academic journal published by Karger Publishers. The journal publishes majorly in the area(s): Renal function & Kidney. It has an ISSN identifier of 1420-4096. It is also open access. Over the lifetime, 2457 publications have been published receiving 44883 citations. The journal is also known as: Kidney and blood pressure research.
Topics: Renal function, Kidney, Kidney disease, Blood pressure, Medicine
Papers published on a yearly basis
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TL;DR: The data support the argument that magnesium supplementation improves the metabolic status in hypomagnesemic CKD patients with pre-diabetes and obesity.
Abstract: Background/Aims: Magnesium is an essential mineral for many metabolic functions. There is very little information on the effect of magnesium supplementation on me
4,639 citations
TL;DR: The effects of GA treatment on plasma phosphate concentration, blood pressure and proteinuria may prove beneficial in chronic renal failure and diabetic nephropathy, and the effect of GA on angiogenin and ß-catenin expression could be exploited for the prophylaxis against colon carcinoma.
Abstract: Gum arabic (GA), a water-soluble dietary fiber rich in Ca2+, Mg2+ and K+, is used in Middle Eastern countries for the treatment of patients with chronic kidney disease
272 citations
TL;DR: Understanding the molecular mechanism, targeting changes in adipocytes and regulating adipokine secretion will help extend therapeutic methods for preventing inflammation and angiogenesis in PD.
Abstract: Chronic inflammation and angiogenesis are the most common complications in patients undergoing maintenance peritoneal dialysis (PD), resulting in progressive peritoneum remolding and, eventually, utrafiltration failure. Contributing to the deeper tissue under the peritoneal membrane, adipocytes play a neglected role in this process. Some adipokines act as inflammatory and angiogenic promoters, while others have the opposite effects. Adipokines, together with inflammatory factors and other cytokines, modulate inflammation and neovascularization in a coordinated fashion. This review will also emphasize cellular regulators and their crosstalk in long-term PD. Understanding the molecular mechanism, targeting changes in adipocytes and regulating adipokine secretion will help extend therapeutic methods for preventing inflammation and angiogenesis in PD.
231 citations
TL;DR: There is progressive narrowing/ obliteration of the postglomerular capillaries which leads to a progressive decrease inglomerular filtration rate and thus to a rise in serum creatinine concentration in diabetic glomerulosclerosis, renal glomerular amyloidosis, decompensated benign nephrosclerosis, secondary malignant nephrosis, and chronic interstitial nephritis.
Abstract: Correlations between the relative volume of the intertubular capillaries in the renal cortex and the serum creatinine concentration in primary glomerulopathies, renal vasculopathies, and chronic interstitial nephritides are reported. In the mesangioproliferative glomerulonephritides, there are significant negative correlations between the number and area of the intertubular capillaries in the cortex and the serum creatinine concentration. In diabetic glomerulosclerosis, renal glomerular amyloidosis, decompensated benign nephrosclerosis, secondary malignant nephrosclerosis, and chronic interstitial nephritis, there is a significant negative correlation between the relative area of the intertubular capillaries and the serum creatinine concentration. Thus, in these diseases, there is progressive narrowing/ obliteration of the postglomerular capillaries which leads to a progressive decrease in glomerular filtration rate and thus to a rise in serum creatinine concentration.
195 citations
TL;DR: In vitro evidence implicate that kruppel-like factor 15 plays an important role and may prove to be an antifibrotic factor in renal interstitial fibrosis through regulation of ERK/MAPK and JNK/ MAPK signaling pathways.
Abstract: Background/Aims: Renal interstitial fibrosis is a hallmark of progressive chronic kidney disease (CKD). Previous studies reported that kruppel-like factor 15 (KLF
174 citations