Showing papers in "Medicinski arhiv in 1990"

Factors which affect patient cooperation in the therapy of hypertension

Abstract: The socio-demographic factors (sex, age, social status and professional qualification), side effects of antihypertensive drugs and the therapeutic effects were compared with patient compliance in a group of 387 hypertensive patients. The results showed that the sociodemographic factors and presence of side effects had no significant influence upon patient compliance. Unlike these factors, therapeutic effects had a significant impact upon patient compliance.

Isolation of viruses from autopsy material during the Coxsackie virus epidemic in Sarajevo in 1985

Abstract: In this paper were presented results of isolation of vira from some organs of the dead newborn infants during the epidemy Coxsackie B virosis in Sarajevo in 1985. 12 newborn died. Obduction was done in seven newborn. From the seven obducated, in six were isolated Coxsackie B-3 vira from heart, lungs, brain, liquor, blood, heart blood but the attempts of isolation of the vira from intestine and from pericardial liquor did not succeed.

The most frequent side effects of adjuvant chemotherapy in patients with breast carcinoma

Abstract: Cytostatics, besides having a desired therapeutic effect on the tumor, also cause side effects which are sometimes a limiting factor in their application. We have observed the type and intensity of side effects of cytostatic therapy suffered by patients with breast cancer during postoperative period (after radical mastectomy) 28 patients have been treated by CMF protocol (cyclophosphamide, methotrexate, 5-fluorouracil) 29 patients by FAC protocol (5-fluorouracil, adriamycin cyclophosphamide) 31 patients by Cooper protocol (cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, prednizon). The patients have been under observation during a six-months period, while they have been submitted to the adjuvant chemotherapy. On the basis of the results obtained, it can be concluded that CMF protocol turned to be best tolerated. Protocol CMF was to a much lesser extent cause to alopecia, paresthesia, vomiting, urogenital disorders as componed to FAC and Cooper protocols. For that reason the adjuvant chemotherapy for patients with breast cancer should start with the CMF protocol, while FAC and Cooper protocols should be saved for the second line of treatment in case of unfavourable reaction to the CMF protocol.