Showing papers in "Neurological Sciences in 1997"
Journal Article•
TL;DR: A linkage and association analysis was made on 14 Italian families with recurrent migraine as discussed by the authors, and five chromosomal regions surrounding the candidate genes 5HT1D (1p36.3-34.3), 5HT2A (13q14-21, 5HT transporter (17q11.2-12), CACNLB1 (17-q 11.2−22), FHM (19p13), and 5HT3B (6q13) were analyzed using 29 DNA polymorphic markers.
Abstract: A linkage and association analysis was made on 14 Italian families with recurrent migraine. We analyzed five chromosomal regions surrounding the candidate genes 5HT1D (1p36.3–34.3), 5HT1B (6q13), 5HT2A (13q14–21), 5HT transporter (17q11.2–12), CACNLB1 (17q11.2–22) and FHM (19p13), using 29 DNA polymorphic markers. All two-point lod scores were negative, and the x2 sib-pair analyses were not significant, thus indicating the probable exclusion of these regions as sites of migraine genes in our population.
25 citations
Journal Article•
TL;DR: In this paper, the cases of two patients with inguinal pain as the only symptom of a T12 metastatic lesion was reported and the patterns of pain referrals from tumor lesions to the spine, epidural space, and spinal cord were reviewed.
Abstract: The cases of two patients with inguinal pain as the only symptom of a T12 metastatic lesion is reported. The patterns of pain referrals from tumor lesions to the spine, epidural space, and spinal cord are reviewed. Focal back pain and pain reported in a distal distribution can both be associated with epidural or cord disease. The differential diagnosis of back pain in patients with cancer can be difficult but may be crucial in differentiating important neurological complications of systemic neoplasms.