Showing papers in "Ophthalmic Genetics in 1991"
TL;DR: The authors compared the incidence and distribution of retinoblastoma in these three prefectures with the figures in Shimabara, and wonder if this similarity is only an accidental coincidence when the historical relationship among the three districts is considered.
Abstract: From 1965 to 1986, thirty-four patients with retinoblastoma were born in Nagasaki Prefecture, Japan, 23 with unilateral and 11 with bilateral retinoblastoma. The incidence of retinoblastoma was calculated to be approximately 1 in 16,053 births; it was bilateral in 1 in 49,618 births. There was no significant difference in the incidence of retinoblastoma between urban and rural areas. In Shimabara district it was 1 in 10,331 births - much higher than in any other district of Nagasaki Prefecture. Historically, almost all the natives had been killed in the Shimabara War in 1637, and then people immigrated to Shimabara mainly from Hyogo, Aichi and Shizuoka Prefectures. The authors compared the incidence and distribution of retinoblastoma in these three prefectures with the figures in Shimabara. The incidence in the Tamba and Tajima districts of Hyogo Prefecture was 1 in 10,570 and 1 in 10,411, respectively, very similar to that in Shimabara. The authors wonder if this similarity is only an accidental coincide...
11 citations
TL;DR: A case of trisomy 13 with microphthalmos and colobomatous cyst of the optic nerve and of the chorioretina with orbital extension, in a six-month-old female patient and the orbital cyst has not increased in size.
Abstract: The authors describe a case of trisomy 13 with microphthalmos and colobomatous cyst of the optic nerve and of the chorioretina with orbital extension, in a six-month-old female patient. The colobomatous cyst has been studied by means of computerized axial tomography and ultrasonography in order to follow its evolution. The orbital cyst has not increased in size.
5 citations