Revista Brasileira De Oftalmologia 

About: Revista Brasileira De Oftalmologia is an academic journal published by Sociedade Brasileira de Oftalmologia. The journal publishes majorly in the area(s): Medicine & Visual acuity. It has an ISSN identifier of 0034-7280. It is also open access. Over the lifetime, 1087 publications have been published receiving 2757 citations.

Dynamic ultra high speed Scheimpflug imaging for assessing corneal biomechanical properties

Abstract: OBJECTIVE: To describe a novel technique for clinical characterization of corneal biomechanics using non-invasive dynamic imaging METHODS: Corneal deformation response during non contact tonometry (NCT) is monitored by ultra-high-speed (UHS) photography The Oculus Corvis ST (Scheimpflug Technology; Wetzlar, Germany) has a UHS Scheimpflug camera, taking over 4,300 frames per second and of a single 8mm horizontal slit, for monitoring corneal deformation response to NCT The metered collimated air pulse or puff has a symmetrical configuration and fixed maximal internal pump pressure of 25 kPa The bidirectional movement of the cornea in response to the air puff is monitored RESULTS: Measurement time is 30ms, with 140 frames acquired Advanced algorithms for edge detection of the front and back corneal contours are applied for every frame IOP is calculated based on the first applanation moment Deformation amplitude (DA) is determined as the highest displacement of the apex in the highest concavity (HC) moment Applanation length (AL) and corneal velocity (CVel) are recorded during ingoing and outgoing phases CONCLUSION: Corneal deformation can be monitored during non contact tonometry The parameters generated provide clinical in vivo characterization of corneal biomechanical properties in two dimensions, which is relevant for different applications in Ophthalmology

Antifungals in eye infections: drugs and routes of administration

Abstract: O tratamento das infeccoes oculares por fungos representa um desafio a pratica oftalmologica. Para obtermos resposta terapeutica adequada, alem do uso da droga correta, e necessaria a administracao desta de forma eficaz. Este manuscrito reune informacoes a respeito das principais drogas antifungicas utilizadas em infeccoes oculares, suas concentracoes e principais vias de administracao.

Assessing ectasia susceptibility prior to LASIK: the role of age and residual stromal bed (RSB) in conjunction to Belin-Ambrósio deviation index (BAD-D)

Abstract: Purpose: To compare the ability to detect preoperative ectasia risk among LASIK candidates using classic ERSS (Ectasia Risk Score System) and Pentacam Belin-Ambrosio deviation index (BAD-D), and to test the benefit of a combined approach including BAD-D and clinical data. Methods: A retrospective nonrandomized study involved preoperative LASIK data from 23 post-LASIK ectasia cases and 266 stable-LASIK (follow up > 12 months). Preoperative clinical and Pentacam (Oculus; Wetzlar, Germany) data were obtained from all cases. Mann-Whitney's test was performed to assess differences between groups. Stepwise logistic regression was used for combining parameters.The areas under the Receiver Operating Characteristic (ROC) curves (AUC) were calculated for all parameters and combinations, with pairwise comparisons of AUC (DeLong's method). Results: Statistically significant differences were found for age, residual stromal bed (RSB), central corneal thickness and BAD-D (p 0.05). ERSS was 3 or more on 12/23 eyes from the ectasia group (sensitivity = 52.17%) and 48/266 eyes from the stable LASIK group (18% false positive). BAD-D had AUC of 0.931 (95% CI: 0.895 to 0.957), with cut-off of 1.29 (sensitivity = 87%; specificity = 92.1%). Formula combining BAD-D, age and RSB provided 100% sensitivity and 94% specificity, with better AUC (0.989; 95% CI: 0.969 to 0.998) than all individual parameters (p>0.001). Conclusion: BAD-D is more accurate than ERSS. Combining clinical data and BAD-D improved ectasia susceptibility screening. Further validation is necessary. Novel combined functions using other topometric and tomographic parameters should be tested to further enhance accuracy.

Bioestatísticas: conceitos fundamentais e aplicações práticas

Abstract: A bioestatistica ganha crescente importância e relevância nos ultimos anos, sendo um dos principais pilares da investigacao cientifica Possui uma serie de conceitos e regras que devem ser bem compreendidos para se realizar ou analisar um artigo Nesta revisao sao abordadas algumas das principais ferramentas utilizadas nos trabalhos de interesse da area oftalmologica, suas aplicacoes e limitacoes