Showing papers in "The American Journal of Medicine in 1961"

TL;DR: Cross validation of the prediction formulas with two sets of independent data demonstrates that the Veterans Administration-Army prediction formulas have retained their reliability and have the highest cross-validation coefficients of any formulas now available.

TL;DR: Although the over-all incidence of malignancy of other organs is not increased in pheochromocytoma, the incidence of carcinoma of the thyroid gland is increased far beyond expectation based on chance concurrence.

TL;DR: Prolonged follow-up of patients receiving a well balanced diet indicates that the endocrine abnormalities of growth and sexual development are reversible.

TL;DR: High serum cholesterol concentrations or hypertension appeared to increase the risk of coronary disease in persons with high serum triglycerides, but by themselves seemed to carry little risk.

TL;DR: All patients with hyperlactatemia except the small group 2B were found to exhibit the various known causes of lactate accumulation consistent with the accompanying changes in blood pyruvate but often only indirectly and incidentally related to the "disease" for which hospital admission was required.

TL;DR: The observations on this family lend much support to previous contentions that the disease will frequently be familial, and it is hoped will stimulate further interest in the assessment of the relatives of subjects found to be affected.

TL;DR: The data lend some support to the suggestion that in some patients corticosteroid may promote transformation of nonnecrotizing to necrotizing arteritis, but the question whether arteritis is a fundamental event in the pathogenesis of arthritis or, alternatively, that arteritis and arthritis are diverse manifestations of rheumatoid disease is not answered.

TL;DR: Functional and metabolic studies have been conducted in a nineteen year old boy who had a lifelong history of progressive weakness upon usage of exercised muscles and severe cramps if exertion was intense or prolonged and a fourfold increase in stored muscle glycogen and no reliably detectable phosphorylase.

TL;DR: Data from clinical, roentgenologic and catheterization studies on thirty patients with a left superior vena cava are presented, showing a higher incidence of arrhythmias during the procedure and difficulty in introducing the catheter past the right atrium.

TL;DR: Although none of the patients was without disease before the onset of lactic acidosis, and some were recovering from serious diseases, they apparently had no features of past history in common and, therefore, none with which the subsequent hyperlactatemia could be said to be associated.

TL;DR: A low axial triradius in the palmar dermal pattern of mongoloid subjects with significant heart malformation was found less frequently than in those with normal hearts, and the importance for prognosis of recognizing such malformation early in life is emphasized.

TL;DR: Electron microscopic and immunochemical findings suggest that there may be differences in the storage form of insulin in different species and in neoplastic beta cells.

TL;DR: A patient with a refractory case of recurrent ventricular tachycardia is described, with striking improvement after bilateral cardiac sympathectomy, followed by normalization of a prolonged QRS conduction time.

TL;DR: Some of the newer immunologic technics are capable of detecting hormones with far greater sensitivity and precision than have yet been demonstrated with most bioassay methods.

TL;DR: Clinical and laboratory data are reported in fifty patients with Cushing's syndrome and the response of the plasma level of the 17-hydroxycorticoids to the intramuscular administration of corticotropin, and also prednisone suppression studies, were of value in establishing the presence or absence of an adrenal tumor before operation.

TL;DR: The development of diffuse interstitial pulmonary fibrosis was observed in two patients with chronic granulocytic leukemia treated with busulfan, and treatment with large doses of prednisone resulted in striking resolution of the pulmonary symptoms and signs.

TL;DR: The charts of 510 patients seen at the Cleveland Clinic with syncope as a major presenting complaint have been reviewed, and 18 different kinds of syncope were identified, and the clinical characteristics of fifteen discussed in detail.

TL;DR: Patients with Cheyne-Stokes respiration had an increased respiratory sensitivity to CO 2, the mean ventilatory CO 2 response being approximately three times the normal, and hyperventilation and respiratory alkalosis, which was the principal cause of hyperpnea.

TL;DR: Patients with a long-standing history of upper gastrointestinal complaints, with or without overt allergies, a roentgenographic picture of a constricting antrum or pylorus, and/or segmental narrowing and dilatation of the small bowel have diffuse eosinophilic gastroenteritis of the monoenteric or polyenteric type.

TL;DR: It is concluded that the standardized glucose tolerance test is the most sensitive diagnostic index and the high incidence of fetal complications of pregnancy in women destined to become diabetic many years later supports the existence of an active metabolic aberration long before the insulogenic mechanism becomes overwhelmed.

TL;DR: Cytomegalic inclusion disease in the colon of a young man with a clinical picture simulating non-specific ulcerative colitis is described in this paper, which appears to be related to a combination of circumstances, perhaps including latent viral infection, reduced immunity incident to debility, disease of the reticuloendothelial system and administration of certain drugs.

TL;DR: It is suggested that the polycythemia occurring in association with cerebellar hemangioblastomas is caused by increased production of red blood cells by the marrow in response to an erythropoiesis stimulating factor produced by the tumor.

TL;DR: It is apparent that this group of drugs are bacteriostatic and fail to eradicate the organism from the host.

TL;DR: The majority of indices of hepatic function returned to normal within one to two weeks following cardiac compensation, except for those reflecting biosynthesis by the liver, which improved more slowly, and hyperglobulinemia, which tended to persist.

TL;DR: The records of 106 patients given the diagnosis of pseudoxanthoma elasticum, angioid streaks, or both (Gronblad-Strandberg syndrome) at the Mayo Clinic from 1931 through 1958 were reviewed.