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Journal ArticleDOI

An evaluation of vasopressor therapy for maternal hypotension during spinal anesthesia.

Francis M. James, +2 more
- 01 Jul 1970 - 
- Vol. 33, Iss: 1, pp 25-34
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TLDR
During hypotension resulting from conduction anesthesia in gravid ewes, uterine blood flow (UBF) decreased roughly in proportion to the decrease in maternal blood pressure and the UBF response was variable, generally increasing but frequently remaining constant or decreasing.
Abstract
During hypotension resulting from conduction anesthesia in gravid ewes, uterine blood flow (UBF) decreased roughly in proportion to the decrease in maternal blood pressure. Ephedrine or mephentermine significantly increased UBF over that accomplished by metaraminol. Presumably, the preferential effe

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Citations
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Journal ArticleDOI

A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery.

TL;DR: This systematic review does not support the traditional idea that ephedrine is the preferred choice for the management of maternal hypotension during spinal anesthesia for elective cesarean delivery in healthy, nonlaboring women.
Journal ArticleDOI

Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery.

TL;DR: Giving phenylephrine alone by infusion at cesarean delivery was associated with a lower incidence of fetal acidosis and maternal nausea and vomiting than giving ephe-drine alone and there was no advantage to combiningphenylephrine and ephedrine.
Journal ArticleDOI

Prevention of Hypotension during Spinal Anesthesia for Cesarean DeliveryAn Effective Technique Using Combination Phenylephrine Infusion and Crystalloid Cohydration

TL;DR: Combination of a high-dose phenylephrine infusion and rapid crystalloid cohydration is the first technique to be described that is effective for preventing hypotension during spinal anesthesia for cesarean delivery.
Journal ArticleDOI

Comparison of phenylephrine infusion regimens for maintaining maternal blood pressure during spinal anaesthesia for Caesarean section

TL;DR: For optimal management, phenylephrine should be titrated to maintain maternal BP at near-baseline values.
Journal ArticleDOI

Prophylactic Phenylephrine Infusion for Preventing Hypotension During Spinal Anesthesia for Cesarean Delivery

TL;DR: Prophylactic phenylephrine infusion is a simple, safe, and effective method of maintaining arterial blood pressure during spinal anesthesia for cesarean delivery.
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