Continuous measurement of peripheral vascular resistance and circulatory function.

TLDR: Peripheral vascular resistance, stroke volume, cardiac output and maximum acceleration were computed in ‘real-time’ using aortic pressure and flow signals processed by simple analogue circuits incorporated into a multichannel recording system.

Abstract: Peripheral vascular resistance, stroke volume, cardiac output and maximum acceleration were computed in ‘real-time’ using aortic pressure and flow signals processed by simple analogue circuits incorporated into a multichannel recording system. The use of the system was exemplified by records of the haemodynamic effects of methoxamine and adrenaline in anaesthetized dogs and noradrenaline, isoprenaline and ephedrine in unanaesthetized dogs. These analogue techniques are applicable to circulatory studies in man.