Histomorphologic pattern of skin lesions in Kathmandu Valley: a retrospective study.

TLDR: Clinico-histopathological correlation was done to see for the inconsistency between clinical and histopathological diagnosis and also to analyse for the false positive diagnosis of melanoma in such lesions.

Abstract: A total of 85 skin biopsies were analyzed to see the pattern of skin disorders in Kathmandu Valley. Clinico-histopathological correlation was done to see for the inconsistency between clinical and histopathological diagnosis and also to analyse for the false positive diagnosis of melanoma in such lesions. The age of the patients ranged from 10 to 88 years. No gender predominance was observed. Five percent of the lesions were located on head and neck region and rest were distributed over chest, back and extremities. Clinically 21 (24.7%) out of 85 cases showed hyperpigmentation and were diagnosed as melanocytic lesions. Intradermal nevus emerged as the single largest disorder with a total of 11 cases (12.9%). Capillary hemangioma cases constituted the second largest group with a total of 9 cases (10.6%). Seborrhoeic Keratosis (8.2%), Verrucous vulgaris (8.2%) Neurofibroma (7.1%), Nonspecific granulomatous lesions (4.7%) and melanoma (3.5%) formed the other major groups of disorders. Morphea (1.2%), Psoriasis (1.2%) and fungal lesions (1.2%) commonly seen in other studies were not found to be common among the skin disorders in the present study.