IgG avidity in the serodiagnosis of acute Toxoplasma gondii infection: a multicenter study
Alessandra Sensini,Susanna Pascoli,Daniela Marchetti,Roberto Castronari,Maurizio Marangi,G. Sbaraglia,Cinzia Cimmino,Alberto Favero,Mariarosa Castelletto,Attilio Mottola +9 more
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TLDR
The IgG avidity test was confirmed as a useful tool in the serodiagnosis of acute T. gondii infection and could be predictive of the stage of infection.About:
This article is published in Clinical Microbiology and Infection.The article was published on 1996-08-01 and is currently open access. It has received 65 citations till now.read more
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Effect of Testing for IgG Avidity in the Diagnosis of Toxoplasma gondii Infection in Pregnant Women: Experience in a US Reference Laboratory
Oliver Liesenfeld,Jose G. Montoya,Jose G. Montoya,Sandra Kinney,Cynthia Press,Jack S. Remington,Jack S. Remington +6 more
TL;DR: Findings highlight the value of testing a single serum sample obtained in the first trimester of pregnancy for IgG avidity, as either the IgM or differential agglutination test in the Toxoplasma serologic profile suggested or was equivocal for a recently acquired infection.
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Improved diagnosis of primary Toxoplasma gondii infection in early pregnancy by determination of antitoxoplasma immunoglobulin G avidity.
TL;DR: Introducing high IgG avidity as a criterion in the first half of pregnancy to exclude the possibility that toxoplasma infection was acquired during gestation, many women will avoid unnecessary examinations, treatment, and anxiety.
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Toxoplasma gondii infection in pregnancy: opportunities and pitfalls of serological diagnosis.
TL;DR: The various factors that should be taken into account when performing serological tests for T. gondii are described, as well as the pitfalls that may be encountered during the interpretative process.
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VIDAS Test for Avidity of Toxoplasma-Specific Immunoglobulin G for Confirmatory Testing of Pregnant Women
Jose G. Montoya,Jose G. Montoya,Oliver Liesenfeld,Sandra Kinney,Cynthia Press,Jack S. Remington,Jack S. Remington +6 more
TL;DR: The findings highlight the value of the VIDAS IgG avidity kit when used in combination with the TSP to exclude recent infection, especially when only a single serum sample is available.
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European multicenter study of the LIAISON automated diagnostic system for determination of Toxoplasma gondii-specific immunoglobulin G (IgG) and IgM and the IgG avidity index.
E. Petersen,M.V. Borobio,Edward Guy,Oliver Liesenfeld,Valeria Meroni,Anne Naessens,Emma Spranzi,Philippe Thulliez +7 more
TL;DR: The LIAISON avidity assay is a valuable assay for the exclusion of recently acquired infection with T. gondii in pregnant women, and it decreases significantly the necessity for follow-up testing.
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Infectious Diseases of the Fetus and Newborn Infant
TL;DR: Infectious diseases of the fetus and newborn infant, Infectious diseases in the fetus as mentioned in this paper, infection of the newborn infant and the mother, infection of a fetus and infection of an infant.
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Toxoplasmosis in Pregnancy
Sin-Yew Wong,Jack S. Remington +1 more
TL;DR: Routine serological screening of women during pregnancy in the United States, although it can successfully detect the acute acquired infection and thereby allow treatment intended to prevent infection of the fetus, is not conducted and a single serum sample is the only source of information on whether the fetus is at risk.
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Recent Primary Toxoplasma Infection Indicated by a Low Avidity of Specific IgG
TL;DR: An unusual IgG avidity assay was developed for the serologic diagnosis of recent primary infection by Toxoplasma gondii and may be used to identify pregnancies that are at risk for congenital toxoplasmosis.
Recent Primary Toxoplasma Infection Indicated by a Low
Klaus Hedman,Maija Lappalainen +1 more
TL;DR: In this paper, an unusual assay was developed for the serologic diagnosis of recent primary infection by Toxoplasma gondii, which measured the antigen-binding avidity of toxoplasma-specific IgG antibodies.
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Fetal toxoplasmosis: outcome of pregnancy and infant follow-up after in utero treatment
Patrick Hohlfeld,Fernand Daffos,Philippe Thulliez,Christian Aufrant,J. Couvreur,J MacAleese,D. Descombey,François Forestier +7 more
TL;DR: It is recommended that spiramycin treatment be started as soon as possible once the diagnosis of maternal Toxoplasma infection during pregnancy is proved or strongly suspected, because a prolonged time interval between onset of infection and start of treatment seems to be associated with the presence of severe fetal lesions at the time of prenatal diagnosis.