Patent
Injectable ceramic compositions and methods for their preparation and use
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TLDR
Injectable implant compositions comprise a biocompatible ceramic matrix present in a fluid carrier, where the ceramic matrix comprises particles having a size distribution in the range from 50 μm to 250 μm.Abstract:
Injectable implant compositions comprise a biocompatible ceramic matrix present in a fluid carrier, where the ceramic matrix comprises particles having a size distribution in the range from 50 μm to 250 μm. Optionally, the compositions may further comprise collagen, where the relative amounts of collagen and ceramic matrix at least partly determine the physical properties of implants formed by injecting the compositions. The fluid carrier is an aqueous buffered medium, typically including an organic polymer base material when there is no collagen present in the composition. The compositions are particularly suitable for repair and augmentation of soft and hard tissues by injection.read more
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References
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Injectable implant composition having improved intrudability
TL;DR: In this article, aqueous suspensions of biomaterials such as cross-linked collagen that contain a biocompatible fluid lubricant, such as glycogen or maltose, are disclosed.
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Inductive collagen-based bone repair preparations
TL;DR: An improved process for the preparation of mineral/collagen/OF inductive implants for bone repair utilizes drying, under ambient pressure conditions, a suspension of 75-95% mineral particles, 5-25% collagen, and an effective amount of OFE or its equivalent wherein the concentration of collagen in the suspension subjected to drying is 30-100 mg/ml as mentioned in this paper.
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Collagen/mineral mixing device and method
TL;DR: A mixing device for inductive and conductive bone repair compositions is described in this paper, along with a method for using the device for preparing such compositions, which provides a simple and rapid method of making a substantially uniform collagen/mineral bone implant preparation.
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Xenogeneic collagen/mineral preparations in bone repair
TL;DR: In this paper, a composition for use in bone repair, in particular in onlay procedures, which comprises calcium phosphate mineral particles in admixture with atelopeptide reconstituted fibrillar collagen preparations is disclosed.
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TL;DR: A permanent, biocompatible material for soft tissue augmentation is described in this paper, which is especially suitable for urethral sphincter augmentation, for treatment of incontinence, for filling soft tissue voids, for creating soft tissue blebs, for the treatment of unilateral vocal cord paralysis and for mammary implants.