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Patent

Method and apparatus for "zeroing" and calibrating a catheter-tip gauge-pressure transducer

TLDR
In this paper, the display is adjusted to a desired value by noting the display indication with the reference side of the transducer at atmospheric pressure, substituting a known offset pressure for atmospheric pressure on the reference-side, to produce a new display indication, and adjusting the display to produce that amount of displacement (between the display indications in steps 1 and 2) which corresponds to the known offsetpressure multiplied by the desired calibration value.
Abstract
Sensitivity or span calibration is adjusted to a desired value by (1) noting the display indication with the reference side of the transducer at atmospheric pressure, (2) substituting a known offset pressure for atmospheric pressure on the reference side, to produce a new display indication, and (3) adjusting the display to produce that amount of displacement (between the display indications in steps 1 and 2) which corresponds to the known offset pressure multiplied by the desired calibration value. With the sensitivity or span calibration adjusted to a desired value, the zero point of the display is adjusted by (1) independently measuring the mean of the actual pressure, (2) noting the mean value of the display indication, and (3) adjusting the zero point to eliminate discrepancy between the mean value of the display and the mean of the actual pressure. The apparatus has a port for a substitute reference pressure, and an external pressure gauge for measuring the mean pressure through an auxiliary lumen of the catheter.

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Citations
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References
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Patent

Pressure sensing device

W Rindner
TL;DR: In this paper, a pressure sensor which produces an electric output proportional to pressure on it is housed in a chamber having a flexible membrane for transmitting external pressure to the sensor, and means are provided for varying the pressure in the chamber by known amounts thus enabling calibration of the pressure sensing system while the sensor is at the site.
Patent

Method and apparatus for zeroing and calibrating an invasive blood pressure monitoring system

Forrest Fox
TL;DR: In this paper, the diaphragm of a strain gauge type blood pressure transducer is subjected to a zero reference pressure for zeroing and an elevated pressure for calibration of a blood pressure monitoring system in order that an oscilloscope display of the blood pressure waveform of the patient may be accurately monitored.
Patent

Blood pressure amplifier with zero balancing means

TL;DR: In this paper, an amplifier for the signal from a blood pressure transducer is balanced to zero reference by introducing its offset signal and an offset balancing or correction signal to a summing amplifier.
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Method and apparatus for testing blood vessel catheters

Joseph Fiore
TL;DR: In this paper, a method and device for testing the pressure readings obtained by a pressure sensing blood vessel catheter connected to a transducer and bedside monitor is presented, which includes a syringe which connects with a tube to provide an airtight test chamber.
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Pressure monitoring system for electrofluidic sensing devices

TL;DR: In this paper, a pressure monitoring system for use with an electrofluidic device for sensing pressure includes a pump (65) for supplying fluid to the EF sensing device (101, 102), and an electrical switching circuit that cyclically causes the supplied pressure to vent when the pressure of supplied fluid inside the sensing device is substantially equal to the applied external pressure.