Patent
Monomeric units useful for reducing the modulus of silicone hydrogels
Kunzler Jay F,Ozark Richard M +1 more
TLDR
In this paper, the subject monomeric units useful in reducing the modulus of hydrogels are disclosed, and they are especially useful in the formation of biomedical articles such as silicone hydrogel contact lenses.Abstract:
Monomeric units useful in reducing the modulus of hydrogels are disclosed. Silicone hydrogels including the subject monomeric units are especially useful in the formation of biomedical articles such as silicone hydrogel contact lenses. In formula (I), A is an activated unsaturated group; R and D independently are alkyl, alkylene or haloalkyl groups having 1 to 10 carbon atoms wherein said carbon atoms may include ether linkages therebetween; R1, R2, R3 and R4 are independently selected from: alkyl or haloalkyl groups wherein ether linkages may be included between carbon atoms; siloxane groups; and carbocyclic ring groups having from 6 to 18 carbon atoms; m is in integer from 1 to 500; n is an integer from 1 to 20; x and y are 0 or 1; z is 1 or 2; and x+y+z=3; so long as at least one of R1 or R2 is an alkyl group having from 1 to 10 carbon atoms.read more
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Patent
Biomedical devices containing internal wetting agents
Kevin P. Mccabe,Frank F. Molock,Hill Gregory A,Azaam Alli,Robert B. Steffen,Douglas G. Vanderlaan,James D. Ford +6 more
TL;DR: In this article, a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer is described, which is used for biomedical applications.
Patent
Soft contact lenses
Douglas G. Vanderlaan,David C. Turner,Marcie Hargiss,Annie C. Maiden,Robert N. Love,James D. Ford,Frank F. Molock,Robert B. Steffen,Hill Gregory A,Azaam Alli,John B. Enns,Kevin P. Mccabe +11 more
TL;DR: In this article, a soft contact lens containing a silicone-hydrogel made by curing a reaction mixture of a silicone containing monomer is described, where the reaction mixture consists of a mixture of reaction mixture and a silicone mixture.
Patent
Hydrogel with internal wetting agent
David C. Turner,Annie C. Maiden,Douglas G. Vanderlaan,Robert B. Steffen,Robert N. Love,James D. Ford,Frank F. Molock,Hill Gregory A,Azaam Alli,Kevin P. Mccabe +9 more
TL;DR: In this paper, a wettable silicone hydrogel made by including a high molecular weight hydrophilic polymer into the mixture of the silicone monomer mix is presented, which is entrapped in the hydrogels with little or no covalent bonding between it and the matrix.
Patent
Surface treatment of silicone hydrogel contact lenses comprising hydrophilic polymer chains attached to an intermediate carbon coating
TL;DR: In this article, an optically clear, hydrophilic coating upon the surface of a silicone medical device by sequentially subjecting the surfaces of the lens to plasma polymerization in a hydrocarbon-containing atmosphere was presented.
Patent
Silicone-containing macromonomers and low water materials
TL;DR: Low water siloxane macromonomers can be copolymerized with unsaturated silicone containing monomers to prepare polymeric materials useful as biomedical devices as discussed by the authors, which are particularly suited for soft contact lens applications.
References
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Patent
Polysiloxane composition and contact lens
TL;DR: Monomeric polysiloxanes end-capped with activated unsaturated groups and polymers and copolymers thereof are disclosed in this article for use as contact lenses with improved properties, such as, oxygen transportability, hydrolytic stability, biological inertness, transparency and improved strength without the use of fillers.
Patent
Novel vinyl carbonate and vinyl carbamate contact lens material monomers
TL;DR: In this paper, the authors proposed novel copolymers useful as hydrogel, soft non-hydrogel and/or rigid gas permeable contact lens materials using the general formula STR 1.
Patent
Novel prepolymers useful in biomedical devices
Yu-Chin Lai,Louis J. Baccei +1 more
TL;DR: A polyurethane based prepolymer is used in biomedical devices which provides high oxygen permeability and superior physical properties as discussed by the authors, but it is not suitable for biomedical applications.
Patent
Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof
Su Kai C,J. Richard Robertson +1 more
TL;DR: In this article, a block copolymer containing polysiloxane and polyoxyalkylene oxide units is described, as well as the preparation thereof and methods of treating vision defects therewith.
Patent
Surface wettable silicone hydrogels
TL;DR: In this article, a novel silicone-containing hydrogel material is disclosed comprising an acrylic-capped polysiloxane prepolymer, polymerized with a bulky poly-siloxanylalkyl(meth)acrylate monomer and at least one hydrophilic monomer.
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