Open AccessBook
On the Mode of Communication of Cholera
TLDR
It would occupy a long time to give an account of the progress of cholera over different parts of the world, with the devastation it has caused in some places, whilst it has passed lightly over others, or left them untouched; and unless this account could be accompanied with a description of the physical condition of the places, and the habits of the people, which I am unable to give, it would be of little use.Abstract:
It would occupy a long time to give an account of the progress of cholera over different parts of the world, with the devastation it has caused in some places, whilst it has passed lightly over others, or left them untouched; and unless this account could be accompanied with a description of the physical condition of the places, and the habits of the people, which I am unable to give, it would be of little use. There are certain circumstances, however, connected with the progress of cholera, which may be stated in a general way. It travels along the great tracks of human intercourse, never going faster than people travel, and generally much more slowly. In extending to a fresh island or continent, it always appears first at a sea-port. It never attacks the crews of ships going from a country free from cholera to one where the disease is prevailing, till they have entered a port, or had intercourse with the shore. Its exact progress from town to town cannot always be traced; but it has never appeared except where there has been ample opportunity for it to be conveyed by human intercourse. There are also innumerable instances which prove the communication of cholera, by individual cases of the disease, in the most convincing manner. Instances such as the following seem free from every source of fallacy. I called lately to inquire respecting the death of Mrs. Gore, the wife of a labourer, from cholera, at New Leigham Road, Streatham. I found that a son of deceased had been living and working at Chelsea. He came home ill with a bowel complaint, of which he died in a day or two. His death took place on August 18th. His mother, who attended on him, was taken ill on the next day, and died the day following (August 20th). There were no other deaths from cholera registered in any of the metropolitan districts, down to the 26th August, within two or three miles of the above place; the nearest beingread more
Citations
More filters
The mechanism for inhibition of Vibrio cholerae virulence gene expression by bile and its fatty acid components
TL;DR: It is indicated that UFAs can enter the bacteria, where they can then interact with ToxT in the cytoplasm to decrease ToxG binding to DNA even at a promoter having only one Tox T binding site, which suggests a mechanism in which UF as do not affect dimerization but can affect monomeric ToxTs binding toDNA.
mechanisms for bicarbonate-mediated virulence in Vibrio cholerae
TL;DR: Bicarbonate was found to increase activation of ToxT-dependent accessory virulence promoters in addition to those that produce CT and TCP, and explains the elevated level of virulence gene transcription.
Dissertation
Mapping risky driver behavior and identifying their contributory factors : a spatial statistical approach
Dissertation
On the Identification and Study of Polycentric Nation Models through the Geosocial Analysis of Social Media Content
TL;DR: The authors published an embargoed version of this work, which will not be publicly available until June 30, 2015, and will be available only for a limited period of time, starting from June 1, 2015.
Dissertation
Systèmes d’Information Géographique et Lien Environnement – Santé (SIGLES) : contribution au développement d'outils cartographiques d'aide à la décision face aux risques sanitaires liés à l'environnement
TL;DR: In this paper, the authors investigate the impact of inegalite tranementales and sociales de sante (IESS) on the degradation of the sante in the region of North-Pas de Calais (NPdC).