Journal ArticleDOI
Practolol in the treatment of ischaemic heart pain. Results of a controlled trial.
Reads0
Chats0
TLDR
A controlled trial of practolol in the treatment of 19 patients with severe coronary heart disease has resulted in highly significant reductions in the frequency of chest pains and consumption of trinitrin tablets.Abstract:
A controlled trial of practolol in the treatment of 19 patients with severe coronary heart disease, manifested by pain at rest as well as with exertion, has resulted in highly significant reductions in the frequency of chest pains and consumption of trinitrin tablets. The incidence of serious unwanted effects, especially heart failure, hypotension, bradycardia and bronchospasm, was very low at the dosage used.read more
Citations
More filters
Journal ArticleDOI
Double-blind comparison of verapamil and practolol in the treatment of angina pectoris
TL;DR: Verapamil proved to be the most efficient drug as regards attack frequency and glyceryl trinitrate consumption as well as physical working capacity, bringing about a statistically significant increase of the exercise tolerance as compared to placebo after a treatment period of four weeks.
References
More filters
Journal ArticleDOI
Relation of Heart Rate and Systolic Blood Pressure to the Onset of Pain in Angina Pectoris
TL;DR: It was concluded that the precipitation of angina is normally the result of a rise in the work of the myocardium to a critical level which is essentially fixed in each patient.
Journal ArticleDOI
Selective blockade of adrenoceptive beta receptors in the heart
D. Dunlop,R. G. Shanks +1 more
Journal ArticleDOI
Assessment of propranolol in angina pectoris. Clinical dose response curve and effect on electrocardiogram at rest and on exercise.
B N Prichard,P M Gillam +1 more
TL;DR: In 6 hypertensive patients in the trial blood pressure fell as dose was increased up to halffull strength, but there was no further fall on doubling to full dose.
Journal ArticleDOI
Alterations in the Circulatory Response to Exercise Following a Meal and Their Relationship to Postprandial Angina Pectoris
TL;DR: The circulatory response to upright bicycle exercise in 12 patients with angina before and after a meal was evaluated to study the mechanisms responsible for the more rapid precipitation of angina in the postprandial state.
Journal ArticleDOI
Practolol in treatment of angina pectoris. A double-blind trial.
TL;DR: A decrease in the mean number of attacks suffered by patients while on practolol and a reduction in the number of glyceryl trinitrate tablets taken, which are of statistical significance at, at least, the 5% level.