Journal ArticleDOI
Role of the chain length of chemically bonded phases and the retention mechanism in reversed-phase liquid chromatography
Gert E. Berendsen,Leo de Galan +1 more
TLDR
In this paper, the influence of the chain length of n-alkyldimethylsilyl bonded phases (RP-1 to RP-22) on retention has been investigated using methanol-water mixtures as the mobile phase.About:
This article is published in Journal of Chromatography A.The article was published on 1980-08-01. It has received 222 citations till now. The article focuses on the topics: Phase (matter).read more
Citations
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Determination of octanol/water partition coefficients for hydrophobic organic chemicals with the “slow‐stirring” method
TL;DR: In this article, the authors presented experimental data on octanol/water partition coefficients for 70 hydrophobic organic chemicals that were determined with a "slow-stirring" method, with high reproducibility and low standard deviations.
Journal ArticleDOI
Prediction of peptide retention times in reversed-phase high-performance liquid chromatography I. Determination of retention coefficients of amino acid residues of model synthetic peptides
TL;DR: In this article, the authors examined the contribution of individual amino acid residues to peptide retention on reversed-phase (RP) columns by measuring their effect on retention of a model synthetic peptide: Ac-Gly-X-X-(Leu)3-(Lys)2-amide, where X is substituted by the 20 amino acids found in proteins.
Journal ArticleDOI
Characterization of bonded phases by solid-state NMR spectroscopy
Klaus Albert,Ernst Bayer +1 more
TL;DR: In this paper, the structure and dynamics of chemically modified silica gels have been investigated by high-resolution solid-state NMR spectroscopy using 29Si cross-polarization and magic angle spinning (CP-MAS).
Journal ArticleDOI
Determination of the Distance Dependence and Experimental Effects for Modified SERS Substrates Based on Self-Assembled Monolayers Formed Using Alkanethiols
TL;DR: In this paper, a modified SERS (surface-enhanced Raman scattering) substrate is used for detecting aromatic compounds, based on self-assembled monolayers (SAMs) formed from compounds such as alkanethiols.
Journal ArticleDOI
Part II. Chromatography using ultra-stable metal oxide-based stationary phases for HPLC.
TL;DR: It is shown, that silanization of the surfaces do not form stable supports for chromatography, and the success of polymer modified surfaces such as polybutadiene (PBD) and polystyrene (PS) is emphasized.
References
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Journal ArticleDOI
Solvophobic interactions in liquid chromatography with nonpolar stationary phases
TL;DR: In this article, the solvophobic theory of solvent interaction with non-polar stationary phases in liquid chromatography is examined on the basis of solvophobia theory and a detailed analysis of the effect of the solvent on this process yields an expression for the capacity factor with essentially no adjustable constants.
Journal ArticleDOI
Gradient selection in reversed-phase liquid chromatography
TL;DR: In this article, a general expression is derived for the numerical calculation of retention data for the case when the relationship between the capacity factor,k, and the mobile phase composition, φ, is known.
Journal ArticleDOI
Hydrophobic effects in reversed-phase liquid chromatography
TL;DR: The role of hydrophobic effects in revered-phase liquid chromatography is examined in this article, where a new topological index, the molecular connectivity, is introduced to represent solute surface area.
Journal ArticleDOI
Influence of organic modifiers on the rentention behaviour in reversed-phase liquid chromatography and its consequences for gradient elution
TL;DR: In this paper, an extensive study of 32 aromatic compounds in aqueous system containing 10-100% of methanol, acetonitrile and tetrahydro-furan as organic modifiers under isocratic conditions is described.
Related Papers (5)
Solvophobic interactions in liquid chromatography with nonpolar stationary phases
Distribution phenomena of mobile-phase components and determination of dead volume in reversed-phase liquid chromatography
R. M. McCormick,Barry L. Karger +1 more