Open AccessJournal Article
Study on the Correlationship between the Content of Combined Anthraquinone and Purgative Action of Steamed Polygonum Multiflorum Thunb.
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In this paper, the content of combined anthraquinone of two specifications (pieces 0.8～ 1 cm, thick slice 2 ～ 4 mm) in steaming by UV spectrophotographic method and to observe purgative actions in rats.Abstract:
Objective To find out the relationship between purgative principles and purgative action after Polygonum multiflorum Thunb.was steamed through high-temperature,so to provide a basis for making quality standards.Methods To determine the content of combined anthraquinone of two specifications(pieces 0.8～1 cm,thick slice 2～4 mm) in steaming by UV spectrophotographic method and to observe purgative actions of two specifications in rats.Results It was the best to steam 6 hours for piece and 4 hours for thick slice without purgative action and the content of combinated anthraquinone was 2.09 mg/g and 2.00 mg/g respectively.Conclusion There is no purgative action after Polygonum multiflorum Thunb.was steamed,the content of combined anthraquinone are significantly lower,so it can be considered combined-anthraquinone as the limited indication of processed Polygonum multiflorum Thunb..read more
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TL;DR: Processing Radix Polygoni Multiflori may change the contents and types of chemicals in it and these changes are probably responsible for the various pharmacological effects of R-RPM and P-R PM as well as hepatotoxicity.
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Comparison of laxative and antioxidant activities of raw, processed and fermented Polygoni Multiflori radix.
TL;DR: All processing procedure, including fermentation, might reduce the anti-oxidative activity of Polygoni Multiflori Radix (PMR), however, most of the processed products could lessen the adverse effect on gastrointestinal tract compared to PMR.
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Integrating Targeted and Untargeted Metabolomics to Investigate the Processing Chemistry of Polygoni Multiflori Radix.
TL;DR: Target and untargeted metabolomics analyses using ultra-performance liquid chromatography-quadrupole/time-of-flight mass spectrometry (UPLC-QTOF-MS/MS) and ultra- Performance Liquid Chromatography- quadrupoles/triple quadrupole mass spectromaetry were integrated were integrated to investigate the processing chemistry of PMR to demonstrate that processing by nine cycles of steaming and drying qualitatively and quantitatively alters the chemical profile ofPMR.
References
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Journal ArticleDOI
Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry
TL;DR: Processing Radix Polygoni Multiflori may change the contents and types of chemicals in it and these changes are probably responsible for the various pharmacological effects of R-RPM and P-R PM as well as hepatotoxicity.
Journal ArticleDOI
Comparison of laxative and antioxidant activities of raw, processed and fermented Polygoni Multiflori radix.
TL;DR: All processing procedure, including fermentation, might reduce the anti-oxidative activity of Polygoni Multiflori Radix (PMR), however, most of the processed products could lessen the adverse effect on gastrointestinal tract compared to PMR.
Journal ArticleDOI
Integrating Targeted and Untargeted Metabolomics to Investigate the Processing Chemistry of Polygoni Multiflori Radix.
TL;DR: Target and untargeted metabolomics analyses using ultra-performance liquid chromatography-quadrupole/time-of-flight mass spectrometry (UPLC-QTOF-MS/MS) and ultra- Performance Liquid Chromatography- quadrupoles/triple quadrupole mass spectromaetry were integrated were integrated to investigate the processing chemistry of PMR to demonstrate that processing by nine cycles of steaming and drying qualitatively and quantitatively alters the chemical profile ofPMR.