Journal ArticleDOI
Synthesis of some N-carboxylic acid derivatives of 3-phenoxypyrrolidines, 4-phenoxypiperidines, and 3-phenoxynortropanes with muscle relaxant and anticonvulsant activities.
Robert F. Boswell,Grover Cleveland Helsley,Robert L. Duncan,William H. Funderburk,David N. Johnson +4 more
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This article is published in Journal of Medicinal Chemistry.The article was published on 1974-09-01. It has received 31 citations till now. The article focuses on the topics: Carboxylic acid & Muscle relaxant.read more
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Journal ArticleDOI
Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis
Juleen Lam,Bruce P. Lanphear,David C. Bellinger,Daniel A. Axelrad,Jennifer McPartland,Patrice Sutton,Lisette Davidson,Natalyn Daniels,Saunak Sen,Tracey J. Woodruff +9 more
TL;DR: There was sufficient evidence supporting an association between developmental PBDE exposure and reduced IQ, and the body of evidence was of “moderate” quality for ADHD with “limited” evidence for an association with PBDEs.
Patent
Cyclic amine compound and pest control agent
TL;DR: A pest control agent characterized by containing as an active ingredient a cyclic amine compound represented by the formula (1): (wherein Cy1 represents an (un)substituted five-membered heterocycle or an unsubstitized group represented by (a): (Y1 and Y2 each independently represent nitrogen or carbon and * indicates the bonding site)), a salt of the compound, or an N-oxide of the compounds as mentioned in this paper.
Patent
1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
Robert M. Jones,Graeme Semple,Fioravanti Beatriz,Guilherme Pereira,Imelda Calderon,Uy Jane,Duvvuri Kameshwari,Choi Jin Sun Karoline,Yifeng Xiong,Dave Vibha,Azimioara Mihai D +10 more
TL;DR: In this article, aryl and heteroaryl derivatives of Fomula (Ia) have been used in the prophylaxis or treatment of metabolic disorders and complications thereof, such as diabetes and obesity.
Patent
Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
Robert M. Jones,Graeme Semple,Yifeng Xiong,Young-Jun Shin,Albert S. Ren,Imelda Calderon,Choi Jin Sun Karoline,Fioravanti Beatriz,Juerg Lehmann,Bruce Marc A +9 more
TL;DR: In this paper, a trisubstituted aryl and heteroaryl derivatives of Formula (I) are used as modulators of metabolism, which are useful in the prophylaxis or treatment of metabolic disorders and complications thereof.
Patent
Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
Robert M. Jones,Graeme Semple,Yifeng Xiong,Young-Jun Shin,Albert S. Ren,Imelda Calderon,Fioravanti Beatriz,Choi Jin Sun Karoline,Carleton R. Sage +8 more
TL;DR: In this paper, the authors proposed a modification of Formula (I) that is useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.