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At what stage of the chick is the zeugopod determined?

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The determination of the zeugopod in chicks occurs during early limb development. Research indicates that the basic morphology of the fibula, a zeugopod bone in the hindlimb, is established during development through the expression of Hox genes, specifically Hoxd11/Hoxd12 . Additionally, studies on limb development in chick embryos show that the fibula emerges from a region defined by a distinct combination of Hox gene expression, which influences the morphology of the zeugopod elements . This early determination of the zeugopod is crucial for the subsequent differentiation and growth of the limb structures. Therefore, the stage at which the zeugopod is determined in chicks aligns with the spatial and temporal patterns of Hox gene expression during limb bud development.

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Open access morphogenese du pied de Fembryon de poulet. Aspects histologiques Par Madeleine Kieny 01 Jan 1975 1 Citations	The zeugopod in chick embryos is determined during the 6.5 to 8-day stage, as indicated by the effects of Vinblastine injection on limb development in the study.
Open access•Posted Content•DOI Quantification reveals early dynamics in Drosophila maternal gradients Alexander Shlemov, Theodore Alexandrov, Nina Golyandina, David M. Holloway, Stefan Baumgartner, Stefan Baumgartner, Alexander V. Spirov, Alexander V. Spirov - Show less +7 more 16 Dec 2020-bioRxiv 1 Citations	Not addressed in the paper.
Open access•Journal Article•DOI Heterochronically early decline of Hox expression prior to cartilage formation in the avian hindlimb zeugopod Namiko Kamiyama, Ryohei Seki, Hitoshi Yokoyama, Koji Tamura - Show less +3 more 01 Aug 2012-Development Growth & Differentiation 10 Citations	The zeugopod in chicks is determined around stages 23-25, as Hoxd11/Hoxd12 expression decreases before cartilage formation, influencing fibula morphology in the hindlimb.
Journal Article•DOI Further observations on the site of bone prospective areas in the chick embryo wing bud R. Amprino 01 Jul 1977-Cells Tissues Organs 2 Citations	The zeugopod in the chick embryo wing bud is determined at a stage anterior to the cranial boundary of the skeletogenous territory of the stylo-zeugopod.
Journal Article•DOI 150 the distribution pattern of primordial germ cells in early chick embryos Yoshiaki Nakamura, Yasuhiro Yamamoto, Fumitake Usui, Tamao Ono, Kumiko Takeda, Keijiro Nirasawa, Hiroshi Kagami, Takahiro Tagami - Show less +7 more 01 Jan 2007-Reproduction, Fertility and Development 1 Citations	The zeugopod is not addressed in the paper.

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