Can You give some information about hexahydrocannabinol?
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Hexahydrocannabinol (HHC) is a cannabinoid compound that has emerged as a "legal" replacement for THC and cannabis. It has been sold as a cheaper alternative to controlled Δ9-THC and is available in various branded and unbranded products, including "legal highs" . HHC is a semi-synthetic cannabinoid derived from hemp extracts, particularly cannabidiol (CBD), through chemical transformations . It has shown effects on the central nervous system, with lower potency than Δ9-THC, and an affinity for the CB1 receptor, suggesting possible therapeutic effects . However, its affinity for the CB1 receptor also indicates a potential for addiction and misuse . The harmful potential of HHC is not well-described due to the lack of effective analytical methods for its detection in biological matrices . HHC has been found in commercial hemp-derived products, but its prevalence and pharmacological properties are still limitedly understood . Additionally, preclinical studies have shown that HHC and its analogs have anti-angiogenic effects, inhibiting tumor growth by targeting VEGF-mediated angiogenesis signaling .
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| Papers (4) | Insight |
|---|---|
| Hexahydrocannabinols (HHCs) are poorly studied cannabinoids found in small concentrations in hemp plants. | |
1 Citations | Hexahydrocannabinol (HHC) is a semi-synthetic cannabinoid derived from hemp extracts and has THC-like pharmacological properties. |
| Hexahydrocannabinol (HHC) is a hydrogenated derivative of tetrahydrocannabinol (THC) that has been sold as a legal replacement to THC and cannabis. | |
| Hexahydrocannabinol (HHC) is a semi-synthetic derivative of cannabidiol (CBD) that is added to cannabis products to produce psychotropic effects similar to Δ9-tetrahydrocannabinol (Δ9-THC). |
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