Search or ask a question

Do diabetics have shorter life expectancy compared to non-diabetic people?

Life expectancy

Type 2 diabetes

Best insight from top research papers

People with diabetes, both type 1 and type 2, generally have a shorter life expectancy compared to non-diabetic individuals. For individuals aged 45, those with type 1 diabetes live on average 13 years less than those without diabetes, while those with type 2 diabetes live around 4 years less . Diabetes remains a significant risk factor for premature death, with approximately 26.6% of deaths in 2019 being of people with diabetes, resulting in around 40,000 excess deaths compared to the general population . Additionally, individuals with type 2 diabetes treated with metformin showed shorter survival times compared to matched controls over a twenty-year period . The mortality associated with both type 1 and type 2 diabetes leads to a loss of future life years, emphasizing the importance of effective engagement with therapy and lifestyle recommendations .

Answers from top 4 papers

PDF

Open Access

More filters

Papers (4)	Insight
Open access•Posted Content•DOI Comparison of long-term effects of metformin on longevity between people with Type 2 diabetes and matched non-diabetic controls 12 Dec 2022	Diabetics, including those treated with metformin, have shorter life expectancy compared to non-diabetic individuals over a twenty-year period, as per the study findings.
Open access•Journal Article•DOI Estimating life years lost to diabetes: outcomes from analysis of National Diabetes Audit and Office of National Statistics data Adrian H. Heald, Mike Stedman, Mark B. Davies, Mark Livingston, Ramadan Alshames, Mark Lunt, Gerry Rayman, Roger Gadsby - Show less +7 more 02 Jun 2020 62 Citations	Diabetics, especially those with T1DM and T2DM, have a shorter life expectancy compared to non-diabetic individuals, resulting in significant life years lost due to the condition.
Open access•Journal Article•DOI People with diabetes have a substantial lower life expectancty Henk Hilderink, René Poos, Chantal J Leemrijse, Marianne Heins - Show less +3 more 01 Oct 2022-European Journal of Public Health	People with diabetes, especially type 1, have a substantially lower life expectancy compared to non-diabetic individuals, with type 1 diabetes associated with a 13-year reduction and type 2 with a 4-year reduction.
Open access•Journal Article•DOI Mortality Rate Associated with Diabetes: Outcomes From a General Practice Level Analysis in England Using the Royal College of General Practitioners (RCGP) Database Indicate Stability Over a 15 Year Period Adrian H. Heald, Mike Stedman, A Robinson, Mark W Davies, K. Livingston, Ramadan Alshames, Gabriela Y C Moreno, Roger Gadsby, Gerry Rayman, Martin Gibson, Simon de Lusignan, Martin Whyte - Show less +11 more 21 Feb 2022-Diabetes Therapy 4 Citations	Diabetics have a stable life years lost compared to non-diabetics, with no significant change over 15 years, indicating a similar life expectancy between the two groups.

My columns

Related Questions

What is the association between lifestyle and mortality risk in people with diabetes?4 answersAdherence to a healthy lifestyle significantly reduces mortality risk in individuals with diabetes. Multiple studies highlight the importance of lifestyle factors such as non-smoking, moderate alcohol consumption, regular physical activity, healthy diet, and optimal body weight in lowering the risk of cardiovascular disease (CVD) mortality, all-cause mortality, and diabetes-related adverse outcomes. The combination of low-risk lifestyle factors was found to be as crucial as achieving ideal blood pressure and glycemic control in preventing diabetes-related complications and mortality. Moreover, a healthy lifestyle was associated with a lower risk of cardiovascular events and mortality in diabetic individuals, emphasizing the significance of promoting healthy habits to reduce the healthcare burden of diabetes.

How does survival bias affect the accuracy of cross-sectional studies in diabetes?5 answersSurvival bias significantly impacts the accuracy of cross-sectional studies in diabetes by underestimating risks associated with the disease. This bias arises from excluding fatal endpoints, leading to a substantial risk underestimation, especially in genotype-dependent survival scenarios. Studies show that misconceptions about diabetes hinder effective management, with factors like low education and specific treatments contributing to prevalent misconceptions among diabetic patients. Additionally, research on death rates among diabetic populations highlights the importance of accurate estimates, with survival ratios and parametric rates aiding in overcoming sampling variations. In epidemiologic studies, length-biased sampling can pose challenges in analyzing time-to-event outcomes, particularly when coupled with censoring, necessitating specialized models for accurate analysis.

Is there a gebetic difference in intelligence between different races?4 answersThere is evidence suggesting that there are genetic differences in intelligence between different races. Studies have shown that intelligence tests are good predictors of school and job performance, and there are common racial/ethnic differences in mean IQ. Based on research, it has been proposed that genetic factors play a role in these differences in general intelligence (g) across different racial or ethnic groups. Twin studies have indicated that intelligence and brain volume have moderate to high heritability for both White and non-White populations, with low variance attributable to shared environment. Additionally, genetic ancestry and education-related polygenic scores have been found to predict both brain volume and intelligence within racial or ethnic groups. These findings support the hypothesis that there are partly genetic causes of intelligence differences between races.

When rate is compared with the diabetic population in other studies examining the prevalence of DRP?3 answersThe prevalence of diabetic retinopathy (DRP) varies when compared with the diabetic population in other studies. In one study by Knudsen et al., the point prevalence of proliferative retinopathy was found to be 0.8% and 0.3% for type 1 and type 2 diabetes, respectively. Another study by Lu et al. reported an overall prevalence of DPN across different countries to be 26.71%, with country-specific prevalences showing considerable variation. Tesfaye and Selvarajah found a prevalence of 28% for DPN in the Eurodiab baseline DPN study. Additionally, Michaelis and Jutzi observed an increase in relative mortality rates in the diabetic population of the GDR, with rates ranging from 466% to 600% in insulin-treated diabetics and from 352% to 528% in non-insulin-treated diabetics. Therefore, the prevalence of DRP can differ depending on the population studied and the specific risk factors considered.

Is the level of serum myeloperoxidase lower in diabetic patients than in non-diabetic patients?3 answersThe level of serum myeloperoxidase is lower in diabetic patients compared to non-diabetic patients.

Are there any differences in the apoptosis of diabetic and non-diabetic cells?5 answersThere are differences in the apoptosis of diabetic and non-diabetic cells. Diabetic cells, specifically β-cells, show increased DNA damage and DNA strand breaks (DSBs), leading to overexpression of p21, a key player in the DNA damage response (DDR) pathway. This overexpression of p21 prevents apoptosis and triggers the p53/p21 cellular response. In the hippocampal CA1 region, diabetes stimulates apoptosis and promotes cell proliferation, leading to increased apoptotic cells and astrocyte cell density in diabetic individuals. Hyperglycemia in cells from children of diabetes mellitus pregnancies (DMPs) also increases apoptosis and affects mRNA expression of genes involved in apoptosis and cellular response. In gingival connective tissue, apoptosis is increased in diabetic patients with chronic periodontitis compared to non-diabetic individuals, suggesting a role for pro-apoptotic proteins in the pathogenesis of periodontal disease in diabetes. Opium addiction has been shown to increase apoptosis in ovary cells, with non-diabetic rats being more susceptible to opium-induced apoptosis than diabetic rats.

See what other people are reading

How often does respondents cut class?

Students cutting class is a prevalent issue in urban high schools, with disengagement and alienation leading to this behavior, often labeled as "boredom". This behavior can result in course failure and dropping out, impacting academic outcomes. Additionally, excessive course dropping is a concern in community colleges, with 13.5% of enrollments resulting in withdrawal, particularly affecting certain student demographics like males, African Americans, and academically underprepared individuals. Understanding attrition in educational settings is crucial, as it can impact data accuracy and student outcomes. Attrition in panel studies can be complex, with respondents missing waves but potentially returning later, highlighting the need for nuanced analytical models to study attrition effectively. Therefore, addressing class cutting and course dropping is essential to improve student engagement and academic success.Impact of population aging on Japan fiscal sustainability?

Population aging in Japan has significant implications for fiscal sustainability. As Japan faces a rapidly aging society with a shrinking working-age population, there is a growing concern about the fiscal burden and sustainability of social security expenditures. Studies suggest that aging populations lead to higher labor income tax rates, increased public debt-to-GDP ratios, and reduced government expenditure-to-GDP ratios. The impact of population aging on regional savings rates in Japan also highlights the shift from positive to negative effects on savings rates due to demographic changes. To address these challenges, policies promoting increased labor supply among females and the elderly, along with enhancing labor productivity, are crucial for mitigating the fiscal pressures caused by demographic aging.What are the prevalence and incidence rates of rheumatic heart disease in the Philippines?

The prevalence and incidence rates of rheumatic heart disease (RHD) in the Philippines are not explicitly provided in the given contexts. However, the contexts do offer insights into the burden of other rheumatic diseases and cardiovascular conditions in the country. Studies highlight the high prevalence of rheumatoid arthritis (RA) among Filipino patients, with a notable female preponderance and significant comorbidities like hypertension and diabetes. Additionally, heart diseases, including ischemic heart disease, are a major health concern in the Philippines, with increasing trends in mortality rates over the years, particularly affecting males, the elderly, and urbanized areas. While specific data on RHD rates are lacking, these findings underscore the significant burden of rheumatic and cardiovascular diseases in the Philippines, warranting further research and public health interventions.What is the World Health Organisation criteria for the classification of of severe acute malnutrition?

The World Health Organization (WHO) criteria for the classification of severe acute malnutrition (SAM) include a weight-for-height Z-score (WHZ) of less than -3SD, bilateral pitting edema, and a mid upper arm circumference (MUAC) of less than 11.5 cm in children aged 6-59 months. SAM can be further categorized as edematous or nonedematous, with edematous malnutrition representing the most severe form of edematous malnutrition, known as Kwashiorkor. Additionally, SAM is diagnosed through anthropometry, considering measurable variables like age, sex, weight, height, and MUAC, with specific criteria for different age groups. The WHO recommends using either MUAC or weight-for-height Z-scores to assess acute malnutrition prevalence, as these criteria may identify different children, and both should be used independently to guide treatment.What is the prevalance of neurodegenerative deseases?

The prevalence of neurodegenerative diseases (NDs) globally is approximately 15% of the population, leading to significant disability. In East Africa, NDs have a high prevalence, impacting life expectancy and quality of life, with a pool estimate proportion of 15.27% among the population studied. NDs are characterized by progressive dysfunction of synapses, neurons, and glial cells, with common disorders including amyloidosis, tauopathies, a-synucleinopathy, and TAR DNA-binding protein 43 proteopathy. Neurodegenerative diseases result in a progressive loss of neuronal cells and decline in central nervous system functions, often leading to dementia, with neuroglia playing fundamental roles in their pathophysiology. The burden of NDs, including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and others, is expected to increase as life expectancies rise globally.What is the issue of burari death of 11 person?

The issue of the Burari death of 11 persons pertains to the occurrence of multiple focal forms of Buruli ulcer, leading to clinical complexities and challenges in surgical management. These cases involved patients with lesions primarily on their limbs, with subsequent development of secondary lesions across various body parts, necessitating multiple surgeries and even amputations for some individuals. Despite successful healing in all patients, post-operative complications like joint stiffness and contractures were observed. Such multifocal forms of Buruli ulcer are considered severe manifestations of the disease, requiring comprehensive surgical interventions and long hospital stays for recovery. Moreover, the incident highlights the critical need for effective healthcare policies and interventions to address complex medical conditions like Buruli ulcer in resource-limited settings, emphasizing the importance of timely and appropriate surgical management to ensure optimal patient outcomes.What is the current state of nutrient profiling research in insecta?

Nutrient profiling research in insects is advancing, with a focus on their diverse nutritional compositions. Insects are rich in proteins, lipids, fibers, minerals, vitamins, and amino acids, making them valuable for human nutrition. However, nutrient content varies based on species, diet, developmental stage, and environmental factors. Studies highlight the potential of insects as alternative protein sources with health-promoting constituents. Despite disparities in nutrient values among species, insects offer significant contributions to the Recommended Daily Allowance and can combat undernutrition. Ongoing research is exploring bioavailability and bioaccessibility of insect nutrients, emphasizing the importance of preparation methods on nutrient availability. This evolving field underscores the potential of insects as sustainable and nutrient-rich food sources for human consumption.How does skipping breakfast affect an individual's daily spending habits?

Skipping breakfast can have a significant impact on an individual's daily spending habits. Research indicates that skipping breakfast is a common practice due to reasons like lack of time and appetite. This behavior can lead to changes in dietary habits, with an increase in eating alone and a decrease in eating with family as the frequency of skipping breakfast rises. Moreover, skipping breakfast is associated with changes in Body Mass Index (BMI) and cognitive abilities, potentially leading to overeating and weight gain, which can have financial implications related to purchasing more food. Therefore, by skipping breakfast, individuals may unknowingly alter their eating patterns and potentially increase their daily spending on food.How educations effect different income groups?

Education plays a crucial role in influencing income levels across different socioeconomic groups. Research indicates that higher education levels are associated with lower income inequality within groups. Moreover, countries with a higher proportion of well-educated individuals tend to exhibit lower income inequality, suggesting that education can help control income disparities. Additionally, the rate of return on education is higher for groups with weaker earning abilities compared to those with stronger abilities, emphasizing the impact of education on income distribution. Therefore, education not only affects individual income but also plays a significant role in shaping income inequality within and between various income groups, highlighting the importance of educational attainment in addressing income disparities.What the role of age in prevalence of diabetic?

The role of age in the prevalence of diabetes is significant and multifaceted, impacting both the global burden of the disease and its management. Age is one of the most important risk factors for type 2 diabetes, with the disease burden being particularly high in older age groups. Studies have shown that the prevalence of diabetes increases with advancing age, with more than half of those with diabetes being aged over 65 years. This trend is attributed to various factors, including changes in glucose homeostasis and the increased longevity of individuals with both type 1 and type 2 diabetes. The global aging population contributes to the rising prevalence of diabetes, with population aging responsible for a significant portion of the growth in global diabetes prevalence over recent decades. However, the increase in diabetes prevalence is not solely due to aging populations; increases in age-specific prevalences, particularly among those aged 45–65, have also played a critical role. This indicates that while aging is a key factor, other demographic and lifestyle factors also contribute to the rising prevalence of diabetes. Moreover, the management and complications of diabetes in older adults present unique challenges. Older individuals with diabetes are more likely to have comorbidities and frailty, complicating their diabetes management. The elderly diabetic population is classified into categories based on their robustness, fragility, and end-of-life status, highlighting the need for individualized care plans. In younger populations, the prevalence of type 2 diabetes is also increasing, particularly among children and adolescents, further emphasizing the role of age in the disease's epidemiology. This younger demographic often presents with a more severe form of the disease, associated with higher degrees of insulin resistance and more rapidly increasing glucose levels. In conclusion, age plays a critical role in the prevalence of diabetes, influencing not only the epidemiology of the disease but also its management and outcomes across different age groups.Does seasons affect heart by-pass patient?

Seasons do have an impact on heart bypass patients, as evidenced by various studies. Research has shown that seasonal variations can influence the outcomes of patients after coronary artery bypass grafting (CABG) surgery, with factors like length of Intensive Care Unit (ICU) stay being affected by the season. Additionally, patients undergoing CABG in different seasons may experience varying rates of postoperative complications such as infection and bleeding. Moreover, seasonal effects have been observed in patients with acute decompensated heart failure (ADHF), with higher admission and mortality rates during colder months. However, in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, seasonal influences may not significantly impact advanced myocardial injury. Overall, understanding and considering seasonal variations are crucial in optimizing the management and outcomes of heart bypass patients.