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Does the type of marital relationship (e.g., single, divorced, widowed) affect the risk of developing rheumatoid arthritis? 


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Different marital statuses like being single, divorced, or widowed do not directly impact the risk of developing rheumatoid arthritis (RA) based on the available research. Factors such as obesity, age, alcoholism, smoking, family history, genetic predisposition, and interactions between family history and smoking play significant roles in the development of RA. Studies have shown that alcoholism and age have a positive association with RA development , while genetic factors like HLA-G gene polymorphisms can influence the risk of RA . Additionally, early identification of predictive factors, including autoantibodies and markers of systemic inflammation, is crucial in treating patients at risk of RA to prevent the progression of the disease . Therefore, while marital status may not directly impact RA risk, other factors like lifestyle, genetics, and early intervention are more influential.

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