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How calculate IC50 of ACacia senegal and boswellia sacra resin on cell line cancer cells?

Boswellia sacra

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The IC50 values for Acacia senegal and Boswellia sacra resin on cancer cell lines can be determined through cytotoxicity assays. For Acacia senegal, in vitro studies showed significant cytotoxic potential against various cancer cell lines. On the other hand, Boswellia sacra resin exhibited cytotoxicity against treatment-resistant breast cancer cells, with the resin from B. sacra showing the most potent effect. Additionally, encapsulating Boswellia sacra oil in PLGA-PCL nanoparticles resulted in a lower IC50 value compared to free oil, indicating enhanced anti-breast cancer effects. Furthermore, Boswellia sacra essential oil demonstrated cytotoxicity against human breast cancer cell lines, with the oil prepared at higher temperatures showing increased potency in inducing cancer cell death. These findings collectively suggest the potential for both Acacia senegal and Boswellia sacra resin to have IC50 values indicative of their cytotoxic effects on cancer cells.

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Open access•Journal Article•DOI Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells Mahmoud M. Suhail, Weijuan Wu, Amy Cao, Fadee G. Mondalek, Kar Ming Fung, Pin Tsen Shih, Pin Tsen Shih, Yu Ting Fang, Yu Ting Fang, Cole Woolley, Gary Young, Hsueh Kung Lin - Show less +11 more 15 Dec 2011-BMC Complementary and Alternative Medicine 138 Citations	Not addressed in the paper.
Open access Anti-cancer action of a new recombinant lectin produced from Acacia species Ayyub Patel, Elsayed E. Hafez, Fahmy G. Elsaid, Mohammed Amanullah, Newborg Elarab - Show less +4 more 01 Jan 2014 6 Citations	Not addressed in the paper.
Open access•Journal Article•DOI Acacia senegal Possesses in vitro Cytotoxicity Against Human Cancer Cells Vikas Sharma 01 Oct 2016-International Journal of Medical Sciences	Not addressed in the paper.
Open access•Journal Article•DOI Comparative Analysis of Pentacyclic Triterpenic Acid Compositions in Oleogum Resins of Different Boswellia Species and Their In Vitro Cytotoxicity against Treatment-Resistant Human Breast Cancer Cells. Michael Schmiech, Sophia J. Lang, Katharina Werner, Luay J. Rashan, Tatiana Syrovets, Thomas Simmet - Show less +5 more 07 Jun 2019-Molecules 28 Citations	Not addressed in the paper.
Open access•Journal Article•DOI Essential Oils Extracted from Boswellia sacra Oleo Gum Resin Loaded into PLGA–PCL Nanoparticles: Enhanced Cytotoxic and Apoptotic Effects against Breast Cancer Cells H. Azzazy, Anwar Abdelnaser, Hadeer Al Mulla, Amany M. Sawy, Samir Shamma, Mahmoud Elhusseiny, S. Alwahibi, N. Mahdy, Sherif A. Fahmy - Show less +8 more 19 Dec 2022-ACS Omega 2 Citations	Not addressed in the paper.

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