How can anisaldehyde and 4 nitroaniline be used to create a ligand?
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Anisaldehyde can be used to create a ligand by reacting it with suitable aldehydes under reductive conditions. Chiral amines can also be used in this process. The resulting ligands based on an imidazole ring with an additional (hetero)ring show strong hydrogen bonds in solution, leading to hindered imidazole tautomerism . These ligands have been applied as ligands in copper (II)-catalyzed nitroaldol reactions, specifically the Henry reaction, and have shown fast reaction times and a reversal in enantioselectivity compared to other chiral amines . However, there is no mention of using 4-nitroaniline specifically in the creation of these ligands in the provided abstracts.
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| The paper does not mention the use of anisaldehyde and 4-nitroaniline in the creation of a ligand. | |
13 Citations | The paper does not provide information on how anisaldehyde and 4-nitroaniline can be used to create a ligand. |
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