How degration of tetracyline happen?
Best insight from top research papers
The degradation of tetracycline can occur through various methods such as photocatalytic activity, plasma treatment, and biocatalytic reactions. C-N-S-tridoped TiO2 composite has shown good photocatalytic activity in degrading tetracycline . Pulsed dielectric barrier discharge (DBD) plasma treatment has been effective in degrading tetracycline by attacking its aromatic ring, amino group, and double bonds with reactive oxygen species . Additionally, FL-Ti3C2Tx has exhibited biocatalytic properties that can degrade tetracycline in the presence of hydrogen peroxide, leading to a colorimetric change in the reaction system . These methods offer efficient pathways for the degradation of tetracycline, which is crucial for mitigating its harmful effects on human health and the environment.
Answers from top 4 papers
More filters
| Papers (4) | Insight |
|---|---|
19 Citations | Degradation of tetracycline is achieved efficiently through solar light-driven process using Fe-EDTA modified g-C3N4 nanosheets, as discussed in the study. |
| Tetracycline degradation occurs through photocatalytic activity on C-N-S-tridoped TiO2 catalyst, forming various intermediates that eventually convert into CO2 and H2O, as shown in the study. | |
20 Citations | Tetracycline degradation occurs in a coaxial-type DBD plasma reactor by attacking its aromatic ring, amino group, and double bonds with hydroxyl radicals and reactive oxygen species, as shown in LC-MS analysis. |
| The provided paper does not mention anything about the degradation of tetracycline. The paper is about Union Carbide's consumer products division and the controversy surrounding the Bhopal plant in India. |
Related Questions
What makes tetracycline, chlortetracycline, and chloramphenicol to degrade easily?5 answersTetracycline, chlortetracycline, and chloramphenicol can degrade easily due to various degradation methods explored in the research papers. Enzymatic catalysis using engineered heme enzymes like YWW Mb has shown high efficiency in degrading tetracycline antibiotics, achieving degradation rates of up to 100% within 5 minutes. Hydrodynamic cavitation (HC) combined with hydrogen peroxide (H2O2) has demonstrated significant degradation of chlortetracycline, with degradation ratios reaching up to 93.8% in 30 minutes. Microbial consortia or individual bacterial strains like Klebsiella pneumoniae CH3 and Bacillus amyloliquefaciens CS1 have also been effective in degrading chlortetracycline, with degradation rates of up to 91.8% observed. Additionally, the Cutaneotrichosporon dermatis strain M503 has shown efficient degradation of tetracycline, doxycycline, and chlorotetracycline under various cultural conditions, proposing putative degradation pathways for these antibiotics.
What are tetracyclines?5 answersTetracyclines are a group of antibiotics with a history spanning over 70 years, known for their broad-spectrum antibacterial activity and additional effects like inhibiting metalloproteinases and displaying anti-inflammatory, anti-apoptotic, and antioxidant properties. Initially used widely in clinical medicine, tetracyclines faced resistance issues, leading to the development of newer compounds like tigecycline, eravacycline, and omadacycline, which bind to the 30S ribosome to inhibit protein synthesis. These antibiotics have a tetracyclic structure and have been modified through chemical semi-synthesis to enhance clinical efficacy, with doxycycline being a commonly used variant. Despite the emergence of resistance due to their extensive use, tetracyclines are still utilized for various infectious diseases, including those caused by multidrug-resistant bacteria, and for conditions like osteoporotic bone loss and skin lesions.
Is tetracycline teratogenic during pegnancy?5 answersTetracycline is suspected to be teratogenic during pregnancy, as mentioned in the abstracts by Elliottand Fearnley. Both authors express concerns about the potential teratogenic effects of tetracycline and recommend caution when prescribing this antibiotic to women of child-bearing age. However, it is important to note that the abstract by Kirjuschenkovstates that tetracycline has been proven to have embryotoxic qualities and is considered highly dangerous during pregnancy. Therefore, based on the available information, it is advisable to avoid the use of tetracycline during pregnancy due to its potential teratogenic effects.
What are the effects of tetracycline on water pollution?5 answersTetracycline (TC) can have adverse effects on water pollution. TC is an essential class of wide-spectrum antibiotics that is widely used in the treatment of bacterial infectious diseases and as growth-promoting additives. TC can contaminate water sources and cause antibiotic resistance, allergic reactions, and other adverse effects in non-target organisms. Various studies have focused on the development of selective and sensitive TC sensors to detect trace quantities of TC in water samples. Metal-organic frameworks (MOFs) have been explored as potential materials for TC detection due to their high selectivity and sensitivity. Additionally, modified biochar derived from waste materials, such as rice waste and sugarcane bagasse, has shown promise in removing TC from water. These adsorbents utilize mechanisms such as pore filling, electrostatic attraction, π-π interactions, and complexation reactions to efficiently remove TC from water. Overall, the presence of TC in water can have detrimental effects, but the development of innovative materials and adsorbents offers potential solutions for water pollution control.
What are some of the unanswered questions about tetracycline destructases?3 answersTetracycline destructases, enzymes that inactivate tetracycline antibiotics, still have unanswered questions surrounding them. One question is the prevalence and dissemination of these enzymes among Gram-negative bacteria in both human and veterinary medicine. Another question is the mechanism of inhibition of type 1 TDases by anhydrotetracycline, a pan-TDase inhibitor. Additionally, the molecular epidemiology and resistance mechanisms of Tet(X) orthologs, which confer high-level tigecycline resistance, need further large-scale epidemiological and functional studies. The transport mechanism of tetracycline and the identification of specific amino acids important for tetracycline transport and substrate specificity in efflux transporters are also areas that require more research. Finally, the selection against resistance caused by the breakdown of tetracycline through enzymatic or non-enzymatic processes raises questions about the biological activities of tetracycline debris.
What are some of the other uses of tetracycline?5 answersTetracycline has various uses beyond its well-established efficacy in treating periodontitis and avulsed teeth. There is growing evidence supporting its use in treating recurrent aphthous stomatitis. Tetracycline can also be conjugated to anti-coagulants and used for preventing or treating plaque-related diseases like atherosclerosis. Additionally, tetracycline can be combined with macrolides to treat various diseases associated with inflammation. Tetracyclines have evolved over time, with newer derivatives showing superior activity against tetracycline-resistant pathogens. They also hold promise as nonantibiotic therapeutic agents, particularly in treating inflammatory and degenerative states in mammalian diseases. Furthermore, tetracyclines have been found to be useful as calpain inhibitors, with potential applications in cellular protection, prevention of cell motility, and treatment of certain infectious diseases.