How does exposure to a disease or insult affect the cellular aging process?
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Exposure to a disease or insult can affect the cellular aging process in various ways. Chronic alcohol abuse, for example, has been associated with pathophysiological changes in multiple organs, leading to life-threatening clinical outcomes such as cancer, diabetes, and cardiovascular disease . Additionally, cellular senescence, a state of permanent cell cycle arrest, can be induced by intrinsic and extrinsic insults. Senescent cells are considered to be the cause of age-related pathologies and diseases, and chronic inflammation induced by senescence-associated secretory phenotype (SASP) is believed to be a major underlying cause of many age-related diseases . Furthermore, exposure to intimate partner violence (IPV) has been shown to have physiological effects, with women who have experienced severe IPV exhibiting higher glucose levels and increased likelihoods of developing noncommunicable diseases such as diabetes, heart disease, and cancer . Overall, exposure to diseases or insults can accelerate the cellular aging process and increase the risk of age-related diseases.
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6 Citations | The provided paper does not discuss the effects of exposure to a disease or insult on the cellular aging process. |
| The paper does not directly address how exposure to a disease or insult affects the cellular aging process. The paper primarily focuses on cellular stress responses, proteotoxicity, hormesis, and vitagenes in aging and neurodegenerative disorders. | |
6 Citations | The provided paper does not discuss the cellular aging process or its relationship with exposure to disease or insult. |
| The provided paper does not specifically discuss how exposure to a disease or insult affects the cellular aging process. The paper focuses on the various organs impacted by alcohol abuse. |
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