How many sequences is clasiffied in cazy database?
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The CAZy database classifies a significant number of sequences related to carbohydrate-active enzymes. As of September 2008, the CAZy database contained over 6400 proteins with assigned EC numbers and 700 proteins with a PDB structure . This database has been continuously updated since 1998 and provides a classification of CAZyme modules based on experimentally characterized proteins, with families populated by related sequences from public databases . The CAZy database has been instrumental in improving functional predictions for numerous genome projects and offers a stable nomenclature for enzymes involved in carbohydrate metabolism . The rapid increase in sequences within the CAZy database due to metagenomics advancements has facilitated better refinement of CAZy families into subfamilies, enhancing the prediction of enzyme functions and molecular engineering possibilities .
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4.9K Citations | The CAZy database classifies sequences based on families, linking them to enzyme specificity and structure; the exact number of sequences is not specified in the provided information. |
| There are 172 GH families in the CAZy database, with four families (GH13, GH57, GH119, and GH126) classified as α-amylase GH families. | |
6K Citations | The CAZy database classifies over 6400 proteins with assigned EC numbers and 700 proteins with a PDB structure, specializing in enzymes related to complex carbohydrates and glycoconjugates. |
01 Jan 2017 41 Citations | The CAZy database classifies sequences of Carbohydrate-Active Enzymes (CAZymes) based on experimentally characterized protein modules, with continuous updates and expert curation since 1998. |
Open access•Journal Article 1 Citations | The CAZy database contains a rapidly increasing number of sequences due to metagenomics advancements, facilitating the refinement of CAZy families into subfamilies for improved function prediction and molecular engineering. |
Related Questions
What are clans in Cazy database and where there are?5 answersClans in the CAZy database refer to groups of families that are evolutionarily related and share a common ancestor. These clans are based on sequence similarities among the carbohydrate-active enzymes (CAZymes) present in the database. The CAZy database classifies CAZymes into families, and these families are further grouped into clans if they exhibit significant sequence similarities, indicating a shared evolutionary history. Clans provide a higher level of organization above families, helping to understand the relationships and evolutionary origins of different CAZyme families. The concept of clans enhances the classification and analysis of CAZymes, contributing to the comprehensive understanding of how these enzymes function and evolve within the context of carbohydrate metabolism.
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