What are some of the advantages Anion Exchange chromatography?5 answersAnion exchange chromatography offers several advantages. It allows for the separation of highly polar compounds, including pharmaceuticals, that cannot be separated using reversed-phase chromatography. It also provides symmetrical peaks with suitable retention times and exclusive selectivity, making it a versatile technique for analysis. Anion exchange chromatography is effective in removing impurities, such as process-related and product-related impurities, during the manufacturing of therapeutic antibodies. Additionally, it can be used for sample purification or preconcentration steps prior to analysis. The method of purifying an insulin precursor using anion exchange chromatography allows for high purity and high yield insulin production by enhancing the binding force of the insulin precursor to the ion exchange resin. Overall, anion exchange chromatography is a valuable tool in various applications, offering efficient separation and purification capabilities.
Who used anion exchange membrane in bioelectrochemical systems?5 answersAnion exchange membranes have been used in bioelectrochemical systems (BESs) by Sleutels et al.and Varcoe et al.. Sleutels et al. studied the transport of cations and anions through ion exchange membranes in BESs and showed that the pH gradient and concentration gradient of other cations determine the total potential loss in cation exchange membranes, while in anion exchange membranes, part of the pH gradient loss can be recovered at the membrane. They also found that microbial electrolysis cells perform better with an anion exchange membrane compared to a cation exchange membrane due to the lower internal resistance of the former. Varcoe et al. provided an up-to-date perspective on the use of anion exchange membranes in BESs, highlighting their application in microbial fuel cells and other energy technologies.
What are the method to prepare hydrous oxide anion exchange membrane ?3 answersThere are several methods to prepare hydrous oxide anion exchange membranes. One method involves using 4,4'-trimethylenedipiperidine (TMDP) as a cross-linking agent. In this method, chloromethylated polysulfone is dissolved in 1-methyl-2-pyrrolidinone (NMP) to obtain a solution, and then TMDP is added to carry out a cross-linking reaction with the chloromethylated polysulfone. N-methylpyrrolidine is then added to carry out a quaternization reaction, resulting in the formation of the anion exchange membrane. Another method involves using a metal hydroxide nanosheet as the base material. The metal hydroxide nanosheet is synthesized and then cast into a membrane. Additionally, a method involves preparing a CSEBS solution and a BPEI solution, and then cross-linking the CSEBS membrane and carrying out quaternization reactions. Finally, a method involves treating the membrane in a strong base to strengthen it and decrease its solubility.
How does water produced in Single chamber MFC using anion exchange membrane ?4 answersWater is produced in a Single chamber MFC using an anion exchange membrane. The membrane allows for the transport of anions, such as hydroxide ions (OH-), which are involved in the electrochemical reactions that occur in the MFC. The anion exchange membrane water electrolysis (AEMWE) technology combines the advantages of proton exchange membrane water electrolysis and traditional alkaline water electrolysis, making it a potentially low-cost and sustainable method for hydrogen production. In the AEMWE process, non-platinum group metal catalysts, such as nickel and cobalt-based oxides, are used for the oxygen evolution reaction (OER). The electrolyte used in the AEMWE operation, such as 1 M KOH, facilitates the transport of hydroxide ions through the anion exchange membrane, resulting in the production of water as a byproduct. The specific composition and properties of the anion exchange membrane, such as the presence of positively charged cyclic amine groups, contribute to its ability to conduct anions and facilitate water production in the MFC.
What is the advantages of ceramic anion exchange membrane ?5 answersCeramic anion exchange membranes offer several advantages. They have a silica-based ceramic coating that provides advantageous performance characteristics in applications requiring selective transport of positively charged ions. The silica-based ceramic contains small pores, which contribute to these advantageous properties. The membranes include quaternary ammonium groups covalently bound to the silica-based ceramic, further enhancing their performance. Ceramic membranes in general have excellent resistance to mechanical, chemical, and thermal stresses, making them highly durable. They can be cleaned by steam sterilization and are resistant to microorganisms. Additionally, ceramic membranes have the possibility of being regenerated through various chemical agents, allowing for the recovery of high permeation flow and reducing exploitation costs.
How can weak anion base exchange resin can be used to purify organic acids?5 answersWeak-base anion exchange resins (WB-AERs) can be used to purify organic acids. These resins have high total exchange capacity and can selectively remove organic acids from aqueous solutions. WB-AERs, such as polyacrylic and polystyrene resins, have been shown to exhibit similar selectivity and higher capacity compared to strong-base (SB) resins. The purification process involves adsorption of the organic acids onto the resin, followed by regeneration using salt-only solutions or organic cosolvents. WB-AERs can be fully protonated under acidic and neutral conditions, functioning similarly to SB-AERs. However, under basic conditions, the removal of organic acids by WB-AERs may decline due to deprotonation of the resin functional groups. Overall, WB-AERs offer a sustainable and cost-effective method for purifying organic acids, with the potential for regeneration and recycling of the resin.