Is 1:1000 adrenaline as a topical haemostat an effective alternative to control bleeding in dentistry and oral surgery?
Best insight from top research papers
Topical 1:1000 adrenaline is not an effective alternative for controlling bleeding in dentistry and oral surgery. Studies have shown that lidocaine with 1:100000 adrenaline-soaked gauze did not provide ideal hemostasis for post-extraction bleeding . Additionally, the combination of adrenaline with cocaine for vasoconstriction and hemorrhage control is potentially dangerous and unnecessary . On the other hand, topical 5% cocaine has been recommended as it achieves the desired effects with fewer side effects . Another study compared different hemostatic agents and found that collagen was the most effective in achieving hemostasis in experimental bone defects . Therefore, it is important to carefully consider the choice of hemostatic agents in oral surgery to ensure successful outcomes and minimize complications .
Answers from top 5 papers
More filters
| Papers (5) | Insight |
|---|---|
| The paper does not specifically mention 1:1000 adrenaline as a topical hemostat. The paper is about the use of topical hemostatic agents in oral surgery. | |
| The answer to the query is not present in the provided paper. The paper is about a non-inferiority trial comparing the safety and efficacy of topical 1:1000 epinephrine to topical 1:10,000 epinephrine in sino-nasal surgeries. | |
1 Citations | The paper does not mention the use of 1:1000 adrenaline as a topical hemostat. The paper evaluates the effects of Alustat, Collagen sponge, and adrenalin on bone healing after endodontic microsurgical procedures. |
17 Citations | The answer to the query is not provided in the paper. The paper discusses the use of a topical adrenaline and cocaine combination for intranasal surgery, but it does not specifically address the use of 1:1000 adrenaline as a topical haemostat in dentistry and oral surgery. |
| The provided paper does not mention the use of 1:1000 adrenaline as a topical haemostat. |
Related Questions
Is there evidence that tranexamic acid irrigation is effective in the management of gastrointestinal bleeding?4 answersTranexamic acid irrigation has been evaluated for the management of gastrointestinal bleeding. The HALT-IT Trial found that tranexamic acid did not improve outcomes in acute gastrointestinal bleeding and may increase the risk of complications. However, a systematic review and meta-analysis of randomized controlled trials showed that tranexamic acid significantly reduced rates of continued bleeding, urgent endoscopic intervention, and mortality compared to placebo in patients with upper gastrointestinal bleeding. The review also highlighted that tranexamic acid is effective in reducing bleeding in various surgical procedures, such as orthopedic surgery, cardiac surgery, and prostate surgery. Further research is needed to clarify the safety and efficacy of tranexamic acid irrigation specifically for gastrointestinal bleeding.
Is tranexamic acid effective in the treatment of gastrointestinal bleeding?5 answersTranexamic acid (TXA) has been shown to be effective in the treatment of gastrointestinal bleeding. Multiple studies have demonstrated that TXA reduces the rate of rebleeding and the need for blood transfusion in patients with upper gastrointestinal bleeding. Additionally, TXA has been found to decrease mortality in patients with gastrointestinal bleeding. However, it is important to note that TXA does not have an effect on mortality associated with severe upper gastrointestinal bleeding. Furthermore, TXA has been shown to be safe and well-tolerated, with no significant adverse effects reported. Overall, the available evidence suggests that early administration of TXA may be recommended for the treatment of upper gastrointestinal bleeding in the emergency department. Further research is needed to determine the effects of TXA on lower gastrointestinal bleeding.
Dosiomics for GI bleeding5 answersDosiomics, a fusion dosimetry technique, has shown promise in the evaluation and management of gastrointestinal (GI) bleeding. It involves combining CT and dose information from different regions of the GI tract to improve prognostic performance. Studies have demonstrated that fusion models incorporating information from both the primary tumor and involved lymph nodes outperform single modality models in predicting recurrence-free survival and metastasis-free survival in nasopharyngeal carcinoma patients. Additionally, interventional radiological treatment options, such as transcatheter arterial embolization and infusion therapy, have been found to be effective in controlling acute GI bleeding. Accurate localization of the bleeding site is crucial for successful management, and imaging methods, both invasive and non-invasive, play an important role in achieving this.
Bleeding on probing. A predictor for the progression of periodontal disease?3 answersBleeding on probing (BOP) has been evaluated as a prognostic indicator for the progression of periodontal disease during the maintenance phase of periodontal therapy. Studies have shown that pockets with a higher incidence of BOP are associated with a higher chance of attachment loss. Patients with a mean BOP of 20% have a significantly lower risk for further loss of probing attachment at single sites compared to patients with a mean BOP of 30%. However, BOP as a predictor of periodontal disease progression has low sensitivity due to a high frequency of false-positive responses. Residual probing depths have been found to be predictive of further disease progression, while persisting bleeding on probing may not be a reliable predictor. Further research is needed to establish the predictive value of BOP in determining the progression of periodontal disease.
What are the effects of adrenaline on female hormones?5 answersAdrenaline has various effects on female hormones. It can inhibit the occurrence of oestrus in mature female mice and prevent the onset of sexual maturity in immature female mice. Adrenaline does not interfere with the action of α-hormone (œstrin) on the uterus and vagina, but it inhibits the action of gonadotropic hormones on the ovary. In an isolated strip of cat uterus, the response to added adrenaline varies depending on the state of the animal in relation to pregnancy. Uteri from virgin cats or non-pregnant cats in oestrus or in anoestrus are inhibited by adrenaline, while uteri from pregnant cats respond to adrenaline with contraction. Adrenaline also affects erythrocyte properties, such as membrane fluidity, acetylcholinesterase enzyme activity, and deformability, in a sex-dependent manner. In summary, adrenaline can have inhibitory effects on female reproductive processes and can modulate erythrocyte properties in a sex-dependent manner.
Oxymethazoline can prevent nose bleeding?5 answersOxymetazoline, an active ingredient in nasal spray decongestants, has clinical utility as a topical hemostatic agent and can be used to minimize postoperative bleeding during ear, nose, and throat surgery. However, there is no specific mention of oxymetazoline's ability to prevent nose bleeding in the abstracts provided.