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Is bachmann bundle a driver of atrial fibrillation fue tonfiber orientation? 


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Bachmann's bundle (BB) is recognized as a crucial structure in atrial fibrillation (AF) due to its role in interatrial conduction and arrhythmogenesis. Studies have shown that BB can be a driver of AF through its unique anatomical and electrophysiological properties, such as conduction velocity and activation patterns . Disruption of BB can lead to interatrial conduction block and subsequent development of atrial tachyarrhythmias . Additionally, interventions targeting BB, such as surgical isolation or ablation, have shown promise in reducing AF relapses and maintaining sinus rhythm in patients with AF . Therefore, BB's structural characteristics and its impact on atrial conduction make it a significant contributor to AF pathophysiology, potentially influenced by fiber orientation and conduction disturbances .

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Bachmann's bundle is implicated in sustaining arrhythmic reentry in atrial fibrillation, making it a potential target in hybrid ablation for long-standing persistent atrial fibrillation.
Premature atrial extrasystoles affect Bachmann's bundle conduction, contributing to atrial fibrillation initiation regardless of their origin, indicating its role in AF independent of fiber orientation.
Bachmann's bundle's fiber orientation may contribute to atrial fibrillation development, as its disruption causes conduction block associated with various atrial arrhythmias and left atrial dysfunction.
Bachmann's bundle may contribute to atrial fibrillation genesis. Surgical isolation of Bachmann's bundle, along with pulmonary veins, can reduce atrial fibrillation relapses, as per the research.
Bachmann's bundle is crucial in atrial fibrillation. Omnipolar Technology can map conduction velocity, aiding in identifying high-speed areas. Fiber orientation's role in AF is not addressed in the paper.

Related Questions

Is the perpendicular fiber orientation change from the bachmann bundle to the left atria a driver of atrial fibrilation?4 answersThe perpendicular fiber orientation change from Bachmann's Bundle (BB) to the left atria is indeed a significant factor in atrial fibrillation (AF) initiation and perpetuation. Studies have shown that premature atrial extrasystoles (AES) originating from various atrial sites, including the left atrial appendage (LAA), can provoke conduction disorders through BB, leading to AF development. Additionally, high-resolution mapping has revealed that a complete transverse line of conduction block across BB is associated with advanced interatrial block (a-IAB), a precursor to AF. Pacing from different atrial sites, such as the right atrial appendage (RAA) and the inferior right atrium, has been shown to impact conduction at BB, with pacing from the inferior right atrium resulting in reduced conduction disorders and total activation time compared to other sites. Therefore, the perpendicular fiber orientation change at BB plays a crucial role in AF pathogenesis.
What is the impact of right atrial function von cardiac power?5 answersRight atrial (RA) function plays a crucial role in cardiac power and patient outcomes. Impaired RA function, particularly the conduit function, has been linked to major adverse cardiac events (MACE) post-acute myocardial infarction (AMI) independently of right ventricular (RV) function. In patients with heart failure (HF), lower RA emptying fraction (RAEF) and increased RA volume index (RAVI) are associated with adverse events, highlighting the significance of RA function in chronic HF populations. Moreover, in precapillary pulmonary hypertension (PH), the RA function index (RAFi) is a strong predictor of clinical failure, improving prognostic power when combined with other established predictors. Therefore, assessing RA function, especially the conduit function and related parameters, is essential for evaluating cardiac power and predicting outcomes in various cardiac conditions.
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