scispace - formally typeset
Search or ask a question

What are benign and renal lesions and role of diagnostic utility? 


Best insight from top research papers

Benign renal lesions refer to non-cancerous abnormalities or growths in the kidney, such as renal cysts, oncocytoma, and angiomyolipoma. These lesions are typically detected incidentally through imaging studies and often do not require further treatment. Diagnostic utility plays a crucial role in accurately identifying and classifying these lesions, guiding clinical management decisions, and determining prognosis. Various imaging modalities, including ultrasound, computed tomography, and magnetic resonance imaging, are used to characterize renal lesions and differentiate between benign and malignant tumors. Additionally, fine needle aspiration (FNA) and needle core biopsy (NCB) are useful methods for diagnosing and subclassifying adult renal masses, showing high accuracy when compared to surgical resections. FNA and NCB can help differentiate between benign and malignant lesions, aiding in treatment planning and determining the need for intervention.

Answers from top 4 papers

More filters
Papers (4)Insight
Open accessBook ChapterDOI
01 Jan 2023
The paper discusses the imaging of renal disease, including benign and malignant lesions. It mentions that various imaging modalities such as ultrasound, CT, and MRI are used for characterization and staging of cystic and solid renal masses. However, it does not specifically mention the role of diagnostic utility for benign and renal lesions.
The paper discusses benign tumors, malignant tumors, and non-neoplastic lesions of the kidney. It emphasizes the importance of accurate diagnosis through multimodality imaging for guiding clinical management and determining prognosis.
The paper discusses various benign renal tumors that can be identified on biopsy material. It mentions that renal cysts are the most common benign renal lesion and need to be distinguished from cystic renal tumors. The role of diagnostic utility is not specifically mentioned in the paper.
The paper discusses the diagnostic utility of renal needle biopsy/FNA in classifying benign renal neoplasms and nonneoplastic mass-forming lesions.

Related Questions

What is the recent challenges in renal tumours pathology?4 answersThe recent challenges in renal tumours pathology include the increasing complexity of classification due to the inclusion of new subtypes and entities, as well as the difficulty in distinguishing between overlapping variants. Immunohistochemistry and genetic studies are being used to aid in the diagnosis of confusing cases and to better classify different variants of renal cell carcinomas (RCCs). There is also a need for additional immunohistochemical and molecular tests to facilitate tumour typing, especially for poorly differentiated metastatic tumours and oncocytic tumours. Interobserver agreement in pathologic staging of renal cancer is relatively good among urologic pathologists, but disagreements still exist, particularly for tumors with small, finger-like protrusions. Mass spectrometry imaging and microproteomics profiling are emerging technologies that show promise in automated tumor classification of renal cancer types, providing a complementary approach to current pathological technologies.
Can radiomics be used to classify breast lesions as benign or malignant?4 answersRadiomics features extracted from breast lesions have shown promise in classifying them as benign or malignant. Variability and robustness of radiomics features were investigated in mammography (MG) images, and it was found that certain features have higher discriminative power and lower dependency on segmentation, making them suitable for automated classification algorithms. A comparison of three radiomics software tools on breast cancer data demonstrated their effectiveness in classifying lesions, with F1-scores exceeding 85%. A radiomics model developed using features extracted from intra- and peri-tumoral regions in dynamic contrast-enhanced MRI showed potential in distinguishing benign from malignant breast lesions, reducing unnecessary biopsies. A comprehensive machine learning tool combining handcrafted radiomics and deep learning models achieved good diagnostic performance in identifying, segmenting, and classifying breast lesions on contrast-enhanced mammography images. Radiomics-based and CNN-based classification models using multi-contrast MRI data showed promising results in classifying breast lesions based on estrogen response and histological subtypes.
What are the clinical features of malignant and benign tumors?5 answersBenign tumors are characterized by their lack of invasion into surrounding tissues and absence of metastasis. They tend to grow slowly and have distinct borders. However, they can cause complications if they become large and compress nearby structures. Common examples include fibroids in the uterus and lipomas in the skin. On the other hand, malignant tumors have the ability to invade and destroy surrounding tissues and can metastasize to distant sites. They tend to grow at a faster rate and have the potential to infiltrate nearby structures. Clinical features of malignant tumors can include a palpable lump/mass, epiphora (excessive tearing), and in the case of lacrimal sac tumors, a mass extending above the medial canthal tendon. Timely diagnosis and intervention for malignant tumors are important due to their infiltrating nature and poor outcomes.
What are the difference betwenn benign and malignant tumor?5 answersBenign tumors are slow-growing and have clear boundaries, while malignant tumors are cancerous and have the ability to invade nearby tissue and spread throughout the body. Benign tumors do not metastasize and remain localized to the area where they originated, whereas malignant tumors can metastasize to other parts of the brain or spinal cord. In terms of appearance, benign tumors have solid boundaries, while malignant tumors have faded boundaries. Both benign and malignant tumors can be life-threatening and result in serious dysfunction of the brain. The optimal treatment of brain tumors depends on their early detection and classification.
What are the differences between benign and malignant tumors?5 answersBenign tumors are slow-growing with clear boundaries and do not spread to other parts of the body. They are considered non-cancerous and less dangerous. On the other hand, malignant tumors are cancerous and have the ability to invade nearby normal tissue and spread throughout the body via the circulatory or lymphatic system. They grow rapidly and can metastasize to other regions of the brain or spinal cord. Malignant tumors are highly dangerous and can result in serious dysfunction of the brain. The boundaries of malignant tumors are not solid in appearance and they appear faded. Benign tumors have solid boundaries or contouring that indicates the particular shade of the tumor. The distinction between benign and malignant tumors is important for determining the optimal treatment and prognosis of brain tumors.
How is a benign tumor diagnosed?5 answersA benign tumor is diagnosed through a combination of imaging procedures and, in some cases, a transcutaneous biopsy. Imaging procedures are used to differentiate between benign and malignant tumors, with specific imaging findings often sufficient for diagnosing most benign tumors. However, some benign tumors may have atypical imaging features, making diagnosis challenging. In cases of diagnostic uncertainty, a transcutaneous liver biopsy can provide clarification. The biopsy involves taking a sample of the tumor tissue for pathological analysis, which is the major method for diagnosing cancer malignancy. The analysis is based on specific features of malignant tissues, such as metastatic cancer cells. However, the traditional diagnosis process can be time-consuming and reliant on expert interpretation. To improve efficiency and accuracy, a novel workflow integrating in vitro primary cancer cell culture and machine learning algorithms has been proposed.

See what other people are reading

What is the current state of research on the application of nanotechnology in the field of neuropsychology?
4 answers
Nanotechnology has significantly impacted neuropsychology research by enhancing diagnostics, therapeutics, and imaging techniques. Researchers have leveraged nanostructured materials to develop advanced bioelectronics interfaces, nanobiosensors, and drug delivery systems tailored for neural tissue processes. Nanoparticles have shown promise in improving neuroimaging modalities by enhancing tissue retention and signal intensity, addressing limitations of conventional contrast agents and radioisotope tracers. Moreover, nanocarrier drug delivery systems have emerged as efficient strategies to overcome the blood-brain barrier, enabling targeted drug delivery to specific regions in the brain for improved treatment outcomes. The application of nanotechnology in neuropsychiatric disorders, such as schizophrenia, bipolar disorder, depression, anxiety disorder, and Alzheimer's disease, holds great potential in revolutionizing pharmacotherapy and treatment modalities for these conditions.
What is the relationship between hypertension and the development of atherosclerosis?
5 answers
Hypertension plays a significant role in the development and progression of atherosclerosis. Studies have shown that elevated blood pressure, even within the high-normal range, can lead to increased atherosclerotic plaque formation. Hypertension not only enhances atherosclerosis in large arteries like the aorta and coronary arteries but also affects small arteries by inducing hyaline arteriolosclerosis. Furthermore, hypertension has been linked to destabilizing plaques, increasing the risk of cardiovascular events and mortality. The relationship between hypertension and atherosclerosis is complex, with hypertension potentially acting as a trigger for atherosclerotic disease due to mechanical stress, leading to a vicious cycle of disease progression. Overall, controlling hypertension is crucial in preventing or delaying the morbidity and mortality associated with atherosclerosis.
Can evaluation of the inferior alveolar nerve in mronj patients?
5 answers
Evaluation of the inferior alveolar nerve in patients with bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be crucial for assessing nerve function. Studies have shown that diagnostic techniques like masseter inhibitory reflex (MIR) can help quantify the extent of inferior alveolar nerve impairment in BRONJ patients, aiding in preoperative and postoperative evaluations. Additionally, three-dimensional imaging techniques, such as magnetic resonance imaging (MRI) with a dedicated dental coil, have been found to be valuable in assessing nerves in the oral cavity, including the inferior alveolar nerve. These imaging modalities provide detailed information about nerve structures, aiding in surgical planning and potentially helping to spare nerves during procedures in oral and maxillofacial surgery.
What is the role of CT perfusion in diffuse liver diseases?
4 answers
CT perfusion plays a crucial role in assessing diffuse liver diseases by providing valuable insights into hemodynamics and tissue characteristics. Studies have shown that CT perfusion parameters like blood flow (BF), blood volume (BV), mean transit time (MTT), and hepatic arterial fraction (HAF) can effectively differentiate between benign and malignant liver pathologies. Additionally, CT perfusion can aid in predicting portal vein thrombosis in patients with liver cirrhosis by analyzing perfusion values like arterial and portal perfusion. Furthermore, CT perfusion has been found to be effective in differentiating fibrosis stages in diffuse liver diseases, especially in cases where ultrasound elastography has limitations. Overall, CT perfusion emerges as a valuable non-invasive tool for characterizing liver pathologies, assessing hemodynamics, and predicting complications in patients with diffuse liver diseases.
How does the comparison of cCT and nCRT interventions in the mesorectal fascia?
4 answers
The comparison between neoadjuvant chemotherapy (nCT) with CAPOX alone and neoadjuvant chemoradiotherapy (nCRT) with capecitabine in the mesorectal fascia (MRF) of locally advanced rectal cancer (LARC) patients shows promising results. Studies indicate that nCT achieves similar rates of pathologic complete response and downstaging as nCRT, with lower incidences of perioperative distant metastasis and preventive ileostomy. Additionally, high-resolution MRI is highlighted as crucial for evaluating tumor infiltration of the mesorectal fascia and the effects of neoadjuvant therapy in locally advanced rectal carcinoma, aiding in patient selection for appropriate treatment. These findings suggest that nCT, particularly with CAPOX, could be an effective alternative to nCRT in LARC cases with uninvolved MRF, potentially improving outcomes and reducing complications.
How diagnostic imaging and radiation safety have become safe?
5 answers
Diagnostic imaging and radiation safety have significantly improved through the implementation of various strategies and guidelines. Key measures include radiation dose optimization techniques, regulatory guidelines, dose monitoring, and education and training programs for healthcare professionals. The principles of radiation protection, such as justification, optimization, and dose limitation, play a crucial role in minimizing unnecessary radiation exposure and reducing risks associated with ionizing radiation. Africa has made strides in raising awareness, applying evidence-based recommendations, establishing diagnostic reference levels, and enhancing education and training opportunities to improve imaging quality and safety. Additionally, advancements in endourological technology have led to less invasive procedures for stone management, emphasizing the importance of protective practices to enhance safety regarding radiation exposure.
Do demyelination and axonal loss can be assessed through electrophysiological assessment to determine the extent of nerve damage?
5 answers
Demyelination and axonal loss can indeed be assessed through electrophysiological evaluations to determine the extent of nerve damage. Electrophysiological measures, such as multimodal evoked potentials (EP) and nerve conduction studies, offer valuable insights into the status of myelination and axonal integrity. These assessments can detect subclinical demyelination, provide early prognostic indicators of therapeutic efficacy in conditions like Multiple Sclerosis (MS), and optimize diagnostic utility in chronic inflammatory demyelinating polyneuropathy (CIDP). Furthermore, longitudinal diffusion MRI-derived fibre-specific measures have shown high sensitivity to axonal loss in MS patients, outperforming traditional measures like brain atrophy and retinal nerve fibre layer thickness. Integrating techniques like optical coherence tomography (OCT) and visual evoked potentials (VEP) can enhance the accuracy of assessing axonal damage or demyelination in conditions like neuromyelitis optica spectrum disorders (NMOSD).
What is the importance of cranial nerves?
5 answers
Cranial nerves play a crucial role in regulating sensory and motor functions of the head and neck, including tasks such as visualization, vocalization, and respiration. They are responsible for transmitting information from sensory organs to the brain and controlling the muscles of various cranial structures. Abnormalities in cranial nerves can lead to a range of disorders affecting the head and neck, emphasizing the importance of understanding their complex anatomy and function. Additionally, cranial nerves are essential for the development of orofacial structures during embryogenesis, with hypoplastic nerves potentially causing developmental abnormalities like Mobius syndrome. Furthermore, the potential role of innervation in regulating stem cells and their niches in various organs and tissues remains an area of exploration, highlighting the broader impact of cranial nerves on tissue repair and homeostasis.
How accurate is FDG PET to diagnose atypical Parkinson?
5 answers
FDG PET has gained importance in diagnosing cardiac sarcoidosis, showing a pooled sensitivity of around 89% and specificity of 78% in untreated patients. In the context of atypical Parkinsonism, accurate and timely diagnosis remains challenging due to overlapping clinical features with idiopathic Parkinson's disease. However, recent advances in MRI technology offer promising imaging modalities for diagnosing atypical Parkinsonian syndromes (APS). While FDG PET is valuable in cardiac sarcoidosis, MRI tools are becoming more appealing for APS diagnosis due to safety, affordability, and accessibility, aligning with updated diagnostic criteria for APS. The use of MRI techniques, alone or in combination, is expected to become common in clinical practice for diagnosing APS accurately and efficiently.
What are the reliability of the findings and are there any limitations?
5 answers
The reliability of findings varies across different studies. In the evaluation of lumbar multifidus myofascial pain syndrome, ultrasound findings showed moderate to very high reliability within and between examiners, indicating good consistency in measuring muscle thickness, thickness changes, and cross-sectional area. Similarly, in the assessment of preoperative MRI findings in lumbar spinal stenosis, there was high inter- and intraobserver agreement among radiologists and spine surgeons for most parameters, except for facet joint osteoarthritis, which showed suboptimal reliability. Conversely, the interrater reliability of physical examination findings in children with suspected community-acquired pneumonia was fair to moderate, with only a few findings demonstrating acceptable levels of reliability, highlighting potential limitations in diagnosing CAP based on examination alone.
What are the current imaging modalities used for brain metastasis detection?
4 answers
The current imaging modalities used for brain metastasis detection include computed tomography (CT) and magnetic resonance imaging (MRI). Advanced imaging techniques such as proton magnetic resonance spectroscopy, magnetic resonance perfusion, diffusion weighted imaging, and diffusion tensor imaging are also utilized to aid in accurate diagnosis, especially in cases of solitary enhancing brain lesions in patients without known malignancy. Additionally, molecular imaging with positron emission tomography (PET) using various agents like 18F-fluorodeoxyglucose (18F-FDG), prostate specific membrane antigen (PSMA) ligands, alkylphosphocholine analogs, and amino acids can help identify brain metastases and improve diagnostic accuracy. Quantitative MRI techniques like diffusion-weighted imaging (DWI), dynamic susceptibility contrast (DSC), arterial spin labeling (ASL), and dynamic contrast-enhanced (DCE) are potential biomarkers for diagnosing metastases recurrence and radioresistance.