What are some examples of dynamic kinetic resolution that doesn't involve enzymes?
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Dynamic kinetic resolution (DKR) reactions that do not involve enzymes have been developed using various organic catalysts. Chiral amines, Brønsted acids, N-heterocyclic carbenes, phosphines, guanidines, and isothioureas are some examples of organic catalysts used in DKR reactions . These reactions have shown high yields and enantioselectivities, making them attractive for the preparation of optically pure molecules from racemic mixtures . Chiral green organocatalysts have also been demonstrated to promote DKRs, expanding the synthetic scope of this concept . Different types of organocatalysts, such as Brønsted acid catalysts, hydrogen-bonding catalysts, N-heterocyclic carbene catalysts, Lewis base catalysts, phase-transfer catalysts, and cinchona alkaloid-based Brønsted base catalysts, have been employed in organocatalytic DKRs . These methodologies allow for the resolution of racemic compounds with quantitative yield and excellent enantioselectivities . Therefore, organocatalytic DKRs offer a wide range of options for achieving dynamic kinetic resolution without the use of enzymes.
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| The paper provides examples of dynamic kinetic resolution reactions catalyzed by various organic catalysts such as chiral amines, Brønsted acids, N-heterocyclic carbenes, phosphines, guanidines, and isothioureas. | |
| The paper does not provide specific examples of dynamic kinetic resolution that do not involve enzymes. | |
| The paper does not provide examples of dynamic kinetic resolution that do not involve enzymes. The paper discusses the chemoenzymatic dynamic kinetic resolution of amines. | |
| The provided paper does not mention any examples of dynamic kinetic resolution that do not involve enzymes. | |
| The paper does not provide specific examples of dynamic kinetic resolution that do not involve enzymes. |
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