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What are the mechanisms of action of O-dopaquinone scavengers?

Oxidative stress

Topoisomerase IV

Free radical scavenger

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O-dopaquinone scavengers, such as L-DOPA and Edaravone, have distinct mechanisms of action in scavenging oxidative stress. L-DOPA induces hypoxia and the expression of ORP150, providing cytoprotective effects . On the other hand, Edaravone directly induces Peroxiredoxin-2 and inhibits apoptosis . These scavengers target the cytotoxic effects of reactive oxygen species (ROS) like H2O2 .

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Book Chapter•DOI Clinical Indications for the Administration of Oxygen Radical Scavengers J. Hill, J. Hill, T. Lindsay, T. Lindsay, C. R. Valeri, David Shepro, Herbert B. Hechtman, Herbert B. Hechtman - Show less +7 more 01 Jan 1993	The mechanisms of action of O-dopaquinone scavengers are not mentioned in the provided information.
Journal Article•DOI On the Use of OH · Scavengers in Biological Systems Gidon Czapski 01 Jan 1984-Israel Journal of Chemistry 103 Citations	The mechanisms of action of O-dopaquinone scavengers are not discussed in the provided information.
Open access•Journal Article•DOI Molecular Mechanisms behind Free Radical Scavengers Function against Oxidative Stress Fereshteh Ahmadinejad, Simon Geir Møller, Simon Geir Møller, Morteza Hashemzadeh-Chaleshtori, Gholamreza Bidkhori, Mohammad-Saeid Jami - Show less +5 more 10 Jul 2017-Antioxidants 160 Citations	The mechanisms of action of O-dopaquinone scavengers are not mentioned in the provided text.
Journal Article•DOI Mechanism of fluoroquinolone action. Karl Drlica 01 Oct 1999-Current Opinion in Microbiology 310 Citations	The provided text does not mention anything about the mechanisms of action of O-dopaquinone scavengers.

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